Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2736911
rs2736911
ARMS2 ; LOC105378525
0.060 GeneticVariation BEFREE Yet, homozygous carriers of a common haplotype carry a premature stop codon in the ARMS2 gene (R38X) and therefore lack ARMS2, but this variant is not associated with AMD. 26427389

2016
dbSNP: rs2736911
rs2736911
ARMS2 ; LOC105378525
0.060 GeneticVariation BEFREE PheWAS results indicate that a nonsense variant in ARMS2 (rs2736911) is associated with age-related macular degeneration (AMD). 25074467

2015
dbSNP: rs2736911
rs2736911
ARMS2 ; LOC105378525
0.060 GeneticVariation BEFREE In the haplotype analysis, C-T of rs2736911-rs10490924 in LOC387715/ARMS2 (OR = 4.85) and C-G of rs551397-rs800292 in CFH (OR = 2.22) predisposed significantly to AMD. 23289807

2013
dbSNP: rs2736911
rs2736911
ARMS2 ; LOC105378525
0.060 GeneticVariation BEFREE These results suggest that variants R38X and the indel are less likely to play a pathogenic role in AMD by changing the level of ARMS2 transcripts. 23942973

2013
dbSNP: rs2736911
rs2736911
ARMS2 ; LOC105378525
0.060 GeneticVariation BEFREE Sensitivity analyses reveal significant association of AMD with rs27</span>36911 in Chinese but not in Caucasian, with c.372_815del443ins54 in Caucasian but not in Chinese, and with rs1049331 in both ethnic groups. 24013816

2013
dbSNP: rs2736911
rs2736911
ARMS2 ; LOC105378525
0.060 GeneticVariation BEFREE R38X variant of ARMS2 seems to be protective from wet ARMD. 22293892

2012