Gene: CFH ×
Source: GWASCAT ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs800292
rs800292
CFH
G 0.900 GeneticVariation GWASCAT We confirmed the association of age-related maculopathy susceptibility 2 (ARMS2) rs10490924 (P=7.38 × 10<sup>-17</sup>), HTRA1 rs11200638 (P=5.47 × 10<sup>-17</sup>) and complement factor H gene (CFH) rs800292 (P=2.53 × 10<sup>-8</sup>) with neovascular AMD, all loci passing the genome-wide significance level (P<5.22 × 10<sup>-8</sup>). 28703135

2017
dbSNP: rs1061170
rs1061170
CFH
C 0.900 GeneticVariation GWASCAT Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. 21665990

2011
dbSNP: rs1061170
rs1061170
CFH
0.900 GeneticVariation GWASCAT Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). 20385826

2010
dbSNP: rs1410996
rs1410996
CFH
0.900 GeneticVariation GWASCAT Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). 20385826

2010
dbSNP: rs1329428
rs1329428
CFH
0.830 GeneticVariation GWASCAT Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration. 20861866

2010
dbSNP: rs1061147
rs1061147
CFH
A 0.810 GeneticVariation GWASCAT Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517

2013
dbSNP: rs380390
rs380390
CFH
C 0.810 GeneticVariation GWASCAT Complement factor H polymorphism in age-related macular degeneration. 15761122

2005
dbSNP: rs10733086
rs10733086
CFH
A 0.800 GeneticVariation GWASCAT Genome-wide analysis of disease progression in age-related macular degeneration. 29346644

2018
dbSNP: rs10737680
rs10737680
CFH
A 0.800 GeneticVariation GWASCAT Seven new loci associated with age-related macular degeneration. 23455636

2013
dbSNP: rs1329424
rs1329424
CFH
T 0.800 GeneticVariation GWASCAT Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. 23326517

2013
dbSNP: rs1831282
rs1831282
CFH
0.800 GeneticVariation GWASCAT Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis. 23577725

2013
dbSNP: rs10801555
rs10801555
CFH
A 0.800 GeneticVariation GWASCAT Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3. 22694956

2012
dbSNP: rs10737680
rs10737680
CFH
A 0.800 GeneticVariation GWASCAT Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 20385819

2010
dbSNP: rs1329424
rs1329424
CFH
T 0.800 GeneticVariation GWASCAT Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 20385819

2010
dbSNP: rs121913059
rs121913059
CFH
0.760 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988

2016
dbSNP: rs35292876
rs35292876
CFH
0.710 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988

2016
dbSNP: rs10922109
rs10922109
CFH
0.700 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988

2016
dbSNP: rs570618
rs570618
CFH
0.700 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988

2016