Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17107315
rs17107315
0.060 GeneticVariation BEFREE We studied 183 unrelated patients with AP and RAP and 168 healthy controls for p.N34S variant in SPINK1 gene using sequencing of genomic DNA. 24844923

2014

dbSNP: rs17107315
rs17107315
0.060 GeneticVariation BEFREE Direct sequencing results indicated the presence of two previously unidentified mutations in exon 2 of PRSS1 (V39E and N42S) in two patients with recurrent acute pancreatitis.Two cases had the N34S SPINK1 mutation. 25206283

2014

dbSNP: rs17107315
rs17107315
0.060 GeneticVariation BEFREE The SPINK1 variant p.N34S is overrepresented in patients with acute pancreatitis, but more studies distinguishing between first-time and recurrent acute pancreatitis have to be done to determine whether this is only true for patients with recurrent acute pancreatitis. 22228370

2012

dbSNP: rs17107315
rs17107315
0.060 GeneticVariation BEFREE SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event. 19888199

2010

dbSNP: rs17107315
rs17107315
0.060 GeneticVariation BEFREE We did not find a statistically significant association of ARP or CP with the N34S SPINK-1 gene mutation. 19844201

2010

dbSNP: rs17107315
rs17107315
0.060 GeneticVariation BEFREE PRSS1 mutations were identified mainly in CP patients (9.6% of CP vs 2.5% of ARP alleles, P = 0.094), whereas N34S SPINK1 mutation was present with comparable frequency in CP and ARP patients (7.7% vs 10.0%, P = 0.768). 16954950

2006