In premenopausal women with IGT</span> (n = 65), associations were found with Lys(109)Argand Lys(656)Asn for overall glucose response to the glucose load.
In postmenopausal women with IGT (n = 24), associations were found with Lys(109)Arg and Lys(656)Asn for fasting insulin (P = 0.05) and with Lys(109)Arg and Gln(223)Arg for the insulin response to an OGTT (P < 0.02).
In premenopausal women with IGT</span> (n = 65), associations were found with Lys(109)Arg and Lys(656)Asnfor overall glucose response to the glucose load.
Two polymorphisms (Lys109Arg, Gln223Arg) in the extracellular domain of the leptin receptor predicted the conversion to type 2 diabetes in high-risk individuals with IGT.
Two polymorphisms (Lys109Arg, Gln223Arg) in the extracellular domain of the leptin receptor predicted the conversion to type 2 diabetes in high-risk individuals with IGT.