|
rs510432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A markedly decreased risk of AA in the recessive models of rs510432 and rs803360 polymorphisms (adjusted odds ratio [OR], 95% confidence interval [CI] = 0.467 [0.236-0.924], P = 0.029 for ATG5 rs510432; adjusted OR [95% CI] = 0.499 [0.255-0.975], P = 0.042 for ATG5 rs803360) was observed.
|
30767262 |
2019 |
|
rs573775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Above all, rs573775 can strongly predict the occurrence of newly onset hematological event in patients with AA.
|
30767262 |
2019 |
|
rs803360
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A markedly decreased risk of AA in the recessive models of rs510432 and rs803360 polymorphisms (adjusted odds ratio [OR], 95% confidence interval [CI] = 0.467 [0.236-0.924], P = 0.029 for ATG5 rs510432; adjusted OR [95% CI] = 0.499 [0.255-0.975], P = 0.042 for ATG5 rs803360) was observed.
|
30767262 |
2019 |
|
rs1800469
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It derived us to the conclusion that the genotype TT of rs1800469 (C/T) was significantly associated with decreased risk of acquired AA (adjusted OR = 0.39, 95% CI = 0.18-0.83, P = 0.014).
|
27933374 |
2017 |
|
rs2069762
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It could be assumed that the rs2069762 polymorphism might reduce the risk of acquired aplastic anemia, while the remaining four SNPs might not contribute to susceptibility to acquired AA in a Chinese population.
|
28268223 |
2017 |
|
rs2317130
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Via the approach of SNaPshot, we genotyped rs1800469 and rs2317130 in 101 patients with acquired AA and 165 controls.
|
27933374 |
2017 |
|
rs1051740
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both mEPHX Tyr113His and His139Arg gene polymorphisms were associated with increased risk of developing AA, and have a significant impact of bad prognosis (p value < 0.01).
|
26999617 |
2016 |
|
rs2234922
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both mEPHX Tyr113His and His139Arg gene polymorphisms were associated with increased risk of developing AA, and have a significant impact of bad prognosis (p value < 0.01).
|
26999617 |
2016 |
|
rs10818488
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TRAF1/C5 rs10818488 polymorphism is not a genetic risk factor for acquired aplastic anemia in a Chinese population.
|
25500258 |
2015 |
|
rs11209026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Arg381Gln variant, which has a strong protective effect against inflammatory bowel disease, showed no association with AA.
|
19165485 |
2009 |
|
rs11465797
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine whether IL-23R single nucleotide polymorphisms (SNPs) might contribute to AA, we selected three IL-23R SNPs with amino acid changes (rs11209026: p.Arg381Gln; rs41313262: p.Val362Ile; and rs11465797: p.Thr175Asn) and compared their frequencies in 279 AA patients and 184 ethnically matched healthy controls.
|
19165485 |
2009 |
|
rs199422295
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Novel heterozygous, non-synonymous mutations in TERT (T726M and G682D) were found in two patients with AA, neither of whom had clinical characteristics suggesting constitutional AA.
|
16627250 |
2006 |