|
rs16906252
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The T allele of the rs16906252 SNP is a key determinant in the acquisition of MGMT methylation in glioblastoma.
|
25910840 |
2015 |
|
rs16906252
|
|
|
0.020 |
GeneticVariation |
BEFREE |
More interestingly, our study demonstrated that a promoter variant, the c.-56C>T (rs16906252) single nucleotide polymorphism (SNP) located within a cis-acting enhancer element at the proximal end of MGMT, is associated with the presence of MGMT promoter methylation in de novo glioblastoma.
|
22975219 |
2013 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our meta-analysis suggested that Arg399Gln polymorphism was associated with increased risk of glioma among Asians and borderline increased risk for glioblastoma among Caucasians, whereas Arg194Trp/Arg280His polymorphisms might have no influence on the susceptibility of glioma in different ethnicities.
|
23383237 |
2013 |
|
rs1695
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We examined GSTP1 Ile105Val polymorphism using PCR-RFLP in 80 astrocytoma and glioblastoma samples.
|
21128213 |
2010 |
|
rs1273593548
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Introduction of normal PTEN together with H-Ras(G12V) into U251 glioblastoma cells reduced the PI3K-dependent activation of Akt, but had no effect on vacuolation.
|
17210246 |
2007 |
|
rs12885300
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs of DIO1 gene (rs2235544) and DIO2 gene (rs12885300) have independent prognostic significance in glioblastoma patients.
|
31452060 |
2019 |
|
rs144551722
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs144551722 SNP was a significant predictor of development of glioblastoma in males (p-value = 0.0056) but not in females even after correction for multiple testing.
|
31556016 |
2019 |
|
rs1982073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Evaluation of rs1982073 polymorphism of transforming growth factor-β1 in glioblastoma.
|
31160907 |
2019 |
|
rs2235544
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs of DIO1 gene (rs2235544) and DIO2 gene (rs12885300) have independent prognostic significance in glioblastoma patients.
|
31452060 |
2019 |
|
rs28357681
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Integrated Approach Reveals Role of Mitochondrial Germ-Line Mutation F18L in Respiratory Chain, Oxidative Alterations, Drug Sensitivity, and Patient Prognosis in Glioblastoma.
|
31323957 |
2019 |
|
rs4644
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation.
|
30341098 |
2019 |
|
rs4652
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNP sites (rs4644 and rs4652) across the <i>LGALS3</i> gene were associated with increased risk for glioblastoma, and the C allele of rs4652 and the A allele of rs4644 could enhance glioblastoma resistance to radio-chemotherapy, but not cell proliferation.
|
30341098 |
2019 |
|
rs1005230
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs1135401891
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we report on the expression of wild-type and L441P variants of human PO in a U87 glioblastoma human cell line in an attempt to assess their effect on glutamate metabolism.
|
29694413 |
2018 |
|
rs11554137
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinical prognostic value of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in glioblastoma.
|
29423539 |
2018 |
|
rs121913343
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biallelic GOF mutations (p.R273H and p.R273C) were identified in a 19-year-old male with glioblastoma (allele frequencies 94% and 48%) and a 54-year-old with pT3 penile squamous cell carcinoma (allele frequencies 19% and 27%).
|
29666004 |
2018 |
|
rs149840192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Studies have shown p.A289V mutation responding to tyrosine kinase inhibitors (TKIs) in glioblastoma cell lines suggesting the point mutation as a potential therapeutic target.
|
30572543 |
2018 |
|
rs2010963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs2440472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between autocrine motility factor receptor gene polymorphism (rs2440472, rs373191257) and glioblastoma multiform in a representative Iranian population.
|
30595704 |
2018 |
|
rs2904551
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we report on the expression of wild-type and L441P variants of human PO in a U87 glioblastoma human cell line in an attempt to assess their effect on glutamate metabolism.
|
29694413 |
2018 |
|
rs3024994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, the VEGF polymorphisms rs3024994, rs2010963, and particularly the homozygous carriers of rs1005230 were associated with a worse prognosis for glioma and glioblastoma.
|
29584591 |
2018 |
|
rs373191257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between autocrine motility factor receptor gene polymorphism (rs2440472, rs373191257) and glioblastoma multiform in a representative Iranian population.
|
30595704 |
2018 |
|
rs833061
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The VEGF polymorphism rs833061 was strongly associated with increased risk for glioma (odds ratio = 164.85) and glioblastoma (odds ratio = 155.66), confirmed after Bonferroni correction.
|
29584591 |
2018 |
|
rs1029044314
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gene expression profiles of three glioma stem cell line samples, three normal astrocyte samples, three astrocyte overexpressing 4 iPSC-inducing and oncogenic factors (myc(T58A), OCT-4, p53DD, and H-Ras(G12V)) samples, three astrocyte overexpressing 7 iPSC-inducing and oncogenic factors (OCT4, H-Ras(G12V), myc(T58A), p53DD, cyclin D1, CDK4(RC24) and hTERT) samples and three glioblastoma cell line samples were downloaded from the ArrayExpress database (accession: E-MTAB-4771).
|
28952134 |
2017 |
|
rs1306185959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gene expression profiles of three glioma stem cell line samples, three normal astrocyte samples, three astrocyte overexpressing 4 iPSC-inducing and oncogenic factors (myc(T58A), OCT-4, p53DD, and H-Ras(G12V)) samples, three astrocyte overexpressing 7 iPSC-inducing and oncogenic factors (OCT4, H-Ras(G12V), myc(T58A), p53DD, cyclin D1, CDK4(RC24) and hTERT) samples and three glioblastoma cell line samples were downloaded from the ArrayExpress database (accession: E-MTAB-4771).
|
28952134 |
2017 |