Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913368
rs121913368
BRAF
0.020 GeneticVariation BEFREE Tumors from patients with BRAF wild-type (WT), V600E (class I), and L597S (class II) metastatic melanoma were used to generate patient-derived xenografts (PDX). 29903896

2018
dbSNP: rs121913368
rs121913368
BRAF
0.020 GeneticVariation BEFREE A patient with BRAF(L597S) mutant metastatic melanoma responded significantly to treatment with the MEK inhibitor, TAK-733. 22798288

2012