Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE This glioma xenograft is the first to display a pure oligodendroglioma histology and expression of R132H. 23527265

2013
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG. 24252742

2013
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE The reported two cases were initially diagnosed as oligodendroglioma with 1p/19q-codeletion and mutation of <i>isocitrate dehydrogenase 1 (IDH1)</i>-R132H. 31508376

2019
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. 25427834

2015
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE The mutation analysis performed on the latter case with DNA separately sampled from the oligodendroglioma- like area and the astrocytoma-like area detected IDH1 G395A in both areas. 22385787

2012
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE Three GBM-O samples had IDH1 (p.R132H) mutations; two of these also demonstrated 1p/19q co-deletion and had a proneural transcriptional profile, a molecular signature characteristic of oligodendroglioma. 26757882

2016
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE The histopathological findings of his surgical specimen revealed characteristics of a low-grade glioma with an IDH1 c.395G>A (R132H) mutation and 1p/19q codeletion, which led to a definitive diagnosis of oligodendroglioma. 29224049

2018
dbSNP: rs121913500
rs121913500
IDH1
0.080 GeneticVariation BEFREE We evaluated nuclear cMYC protein levels and IDH1 (R132H) by immunohistochemistry in patients with oligodendroglioma/oligoastrocytomas (n = 20), astrocytomas (grade II) (n = 19), anaplastic astrocytomas (n = 21) or glioblastomas (n = 111). 23934175

2013
dbSNP: rs113488022
rs113488022
BRAF
0.030 GeneticVariation BEFREE Genetic analyses revealed amplification of the BRAF gene in both the primary cerebellar pilocytic astrocytoma and the recurrent tumor with biphasic features, as well as a BRAF V600E missense mutation in the oligodendroglioma-like component. 23082883

2013
dbSNP: rs113488022
rs113488022
BRAF
0.030 GeneticVariation BEFREE A BRAF(V600E) mutation was also detected in one oligodendroglioma, and a BRAF(A598V) in one diffuse astrocytoma. 22568401

2012
dbSNP: rs113488022
rs113488022
BRAF
0.030 GeneticVariation BEFREE BRAF V600E mutant oligodendroglioma-like tumors with chromosomal instability in adolescents and young adults. 31630459

2019
dbSNP: rs118101777
rs118101777
IDH2
0.030 GeneticVariation BEFREE ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. 25427834

2015
dbSNP: rs118101777
rs118101777
IDH2
0.030 GeneticVariation BEFREE Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG. 24252742

2013
dbSNP: rs118101777
rs118101777
IDH2
0.030 GeneticVariation BEFREE Three GBM-O samples had IDH1 (p.R132H) mutations; two of these also demonstrated 1p/19q co-deletion and had a proneural transcriptional profile, a molecular signature characteristic of oligodendroglioma. 26757882

2016
dbSNP: rs121913377
rs121913377
BRAF
0.030 GeneticVariation BEFREE A BRAF(V600E) mutation was also detected in one oligodendroglioma, and a BRAF(A598V) in one diffuse astrocytoma. 22568401

2012
dbSNP: rs121913377
rs121913377
BRAF
0.030 GeneticVariation BEFREE Genetic analyses revealed amplification of the BRAF gene in both the primary cerebellar pilocytic astrocytoma and the recurrent tumor with biphasic features, as well as a BRAF V600E missense mutation in the oligodendroglioma-like component. 23082883

2013
dbSNP: rs121913377
rs121913377
BRAF
0.030 GeneticVariation BEFREE BRAF V600E mutant oligodendroglioma-like tumors with chromosomal instability in adolescents and young adults. 31630459

2019
dbSNP: rs55819519
rs55819519
TP53
0.030 GeneticVariation BEFREE Three GBM-O samples had IDH1 (p.R132H) mutations; two of these also demonstrated 1p/19q co-deletion and had a proneural transcriptional profile, a molecular signature characteristic of oligodendroglioma. 26757882

2016
dbSNP: rs55819519
rs55819519
TP53
0.030 GeneticVariation BEFREE We evaluated nuclear cMYC protein levels and IDH1 (R132H) by immunohistochemistry in patients with oligodendroglioma/oligoastrocytomas (n = 20), astrocytomas (grade II) (n = 19), anaplastic astrocytomas (n = 21) or glioblastomas (n = 111). 23934175

2013
dbSNP: rs55819519
rs55819519
TP53
0.030 GeneticVariation BEFREE The reported two cases were initially diagnosed as oligodendroglioma with 1p/19q-codeletion and mutation of <i>isocitrate dehydrogenase 1 (IDH1)</i>-R132H. 31508376

2019
dbSNP: rs1034749666
rs1034749666
OLIG2
0.010 GeneticVariation BEFREE Molecular cytogenetic analyses demonstrated chromosomal losses of 1p and 19q and a mutation of isocitrate dehydrogenase 1 (G395A, R132H) in both the oligodendroglioma and gangliocytoma areas. 24054724

2013
dbSNP: rs1042522
rs1042522
TP53
0.010 GeneticVariation BEFREE In stratified analyses by ethnicity, source of controls, and glioma subtypes, the p53 codon 72 Arg/Pro polymorphism did not alter the risk for glioma in population-based, hospital-based, astrocytoma, and oligodendroglioma studies among Caucasian. 23860773

2013
dbSNP: rs11133391
rs11133391
CLOCK
0.010 GeneticVariation BEFREE The variant allele for CLOCK rs11133391 under a recessive model increased risk of oligodendroglioma (OR 2.41; 95 % CI 1.31-4.42; p = 0.005), though not other glioma subtypes (p for heterogeneity = 0.0033). 24135790

2014
dbSNP: rs1131691014
rs1131691014
TP53
0.010 GeneticVariation BEFREE In stratified analyses by ethnicity, source of controls, and glioma subtypes, the p53 codon 72 Arg/Pro polymorphism did not alter the risk for glioma in population-based, hospital-based, astrocytoma, and oligodendroglioma studies among Caucasian. 23860773

2013
dbSNP: rs1131691021
rs1131691021
TP53
0.010 GeneticVariation BEFREE A c.515G>T (p.R172M) mutation of the IDH2 gene was only identified in a grade II oligodendroglioma patient which was wild-type for IDH1. 21643842

2011