|
rs10419226
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs10419226
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs11789015
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs11789015
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs2342002
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs2342002
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs2687201
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs2687201
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs13429103
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
Ever smoking was associated with an almost 12-fold increase in risk of EA among individuals with rs13429103-AA genotype (odds ratio=11.82; 95% CI, 4.03-34.67).
|
29551738 |
2018 |
|
rs13429103
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Ever smoking was associated with an almost 12-fold increase in risk of EA among individuals with rs13429103-AA genotype (odds ratio=11.82; 95% CI, 4.03-34.67).
|
29551738 |
2018 |
|
rs17451754
|
|
G |
0.710 |
GeneticVariation |
GWASCAT |
We identified eight new risk loci associated with either Barrett's oesophagus or oesophageal adenocarcinoma, within or near the genes CFTR (rs17451754; p=4·8 × 10<sup>-10</sup>), MSRA (rs17749155; p=5·2 × 10<sup>-10</sup>), LINC00208 and BLK (rs10108511; p=2·1 × 10<sup>-9</sup>), KHDRBS2 (rs62423175; p=3·0 × 10<sup>-9</sup>), TPPP and CEP72 (rs9918259; p=3·2 × 10<sup>-9</sup>), TMOD1 (rs7852462; p=1·5 × 10<sup>-8</sup>), SATB2 (rs139606545; p=2·0 × 10<sup>-8</sup>), and HTR3C and ABCC5 (rs9823696; p=1·6 × 10<sup>-8</sup>).
|
27527254 |
2016 |
|
rs17451754
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We identified eight new risk loci associated with either Barrett's oesophagus or oesophageal adenocarcinoma, within or near the genes CFTR (rs17451754; p=4·8 × 10<sup>-10</sup>), MSRA (rs17749155; p=5·2 × 10<sup>-10</sup>), LINC00208 and BLK (rs10108511; p=2·1 × 10<sup>-9</sup>), KHDRBS2 (rs62423175; p=3·0 × 10<sup>-9</sup>), TPPP and CEP72 (rs9918259; p=3·2 × 10<sup>-9</sup>), TMOD1 (rs7852462; p=1·5 × 10<sup>-8</sup>), SATB2 (rs139606545; p=2·0 × 10<sup>-8</sup>), and HTR3C and ABCC5 (rs9823696; p=1·6 × 10<sup>-8</sup>).
|
27527254 |
2016 |
|
rs9823696
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
The locus identified near HTR3C and ABCC5 (rs9823696) was associated specifically with oesophageal adenocarcinoma (p=1·6 × 10<sup>-8</sup>) and was independent of Barrett's oesophagus development (p=0·45).
|
27527254 |
2016 |
|
rs9823696
|
|
|
0.710 |
GeneticVariation |
BEFREE |
The locus identified near HTR3C and ABCC5 (rs9823696) was associated specifically with oesophageal adenocarcinoma (p=1·6 × 10<sup>-8</sup>) and was independent of Barrett's oesophagus development (p=0·45).
|
27527254 |
2016 |
|
rs3784262
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Meta-analysis of all data identified another SNP associated with BE and esophageal adenocarcinoma: rs3784262, within ALDH1A2 (OR = 0.90; 95% CI: 0.87-0.93; P = 3.72 × 10(-9)).
|
25447851 |
2015 |
|
rs3784262
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
|
24121790 |
2013 |
|
rs11901649
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.
|
31527586 |
2019 |
|
rs4676893
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.
|
31527586 |
2019 |
|
rs12465911
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Three SNPs (rs12465911, rs2341926, rs13396805) at chromosome 2q23.3, near the RND3-RBM43 gene, interacted with GERD symptoms (P = 1.70×10<sup>-7</sup>, P = 1.83×10<sup>-7</sup>, and P = 3.58×10<sup>-7</sup>, respectively) to affect risk of EA.
|
29551738 |
2018 |
|
rs17002540
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.
|
29551738 |
2018 |
|
rs2434584
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.
|
29551738 |
2018 |
|
rs2971030
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.
|
29551738 |
2018 |
|
rs7141987
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.
|
29551738 |
2018 |
|
rs10108511
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
We identified eight new risk loci associated with either Barrett's oesophagus or oesophageal adenocarcinoma, within or near the genes CFTR (rs17451754; p=4·8 × 10<sup>-10</sup>), MSRA (rs17749155; p=5·2 × 10<sup>-10</sup>), LINC00208 and BLK (rs10108511; p=2·1 × 10<sup>-9</sup>), KHDRBS2 (rs62423175; p=3·0 × 10<sup>-9</sup>), TPPP and CEP72 (rs9918259; p=3·2 × 10<sup>-9</sup>), TMOD1 (rs7852462; p=1·5 × 10<sup>-8</sup>), SATB2 (rs139606545; p=2·0 × 10<sup>-8</sup>), and HTR3C and ABCC5 (rs9823696; p=1·6 × 10<sup>-8</sup>).
|
27527254 |
2016 |
|
rs1247942
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.
|
27527254 |
2016 |