| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | Epithelioid glioblastoma is a recognized glioblastoma variant, recently added to the World Health Organization brain tumor classification, with similar prognosis as the classic variant and B-Raf V600E mutations in 50% of the cases. | 31258848 | 2019 |
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0.080 | GeneticVariation | BEFREE | Here, we describe a case of systemic metastases of a clonal subpopulation of BRAF V600E mutated glioblastoma in a patient previously treated with surgery, radiation, temozolomide and bevacizumab. | 29744614 | 2018 |
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|
0.080 | GeneticVariation | BEFREE | BRAF V600E mutation and BRAF VE1 immunoexpression profiles in different types of glioblastoma. | 30013630 | 2018 |
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|
0.080 | GeneticVariation | BEFREE | This case suggests that the BRAF V600E mutation may be involved in the malignant transformation to glioblastoma. | 26404554 | 2016 |
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|
0.080 | GeneticVariation | BEFREE | An institutional cohort of 105 brain tumors (51 dysembryoplastic neuroepithelial tumors (DNTs), 14 subependymal giant cell astrocytomas (SEGAs), 12 glioblastoma with neuronal marker expression (GBM-N), and 28 pleomorphic xanthoastrocytomas (PXAs)) from 100 patients were investigated for the presence of BRAF(V600E) by direct sequencing. | 25346165 | 2015 |
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0.080 | GeneticVariation | BEFREE | Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy. | 24725538 | 2014 |
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0.080 | GeneticVariation | BEFREE | Here, ten PAs with atypical clinicoradiologic and histologic features and six pediatric glioblastoma multiforme (pGBMs) were analyzed for BRAF V600E, IDH1, IDH2, and TP53 mutations. | 24057326 | 2013 |
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0.080 | GeneticVariation | BEFREE | In our analysis we detect BRAF V600E mutations in 12 of 20 (60%) WHO grade II PXA, in 1 of 6 (17%) PXA with anaplasia and in 1 glioblastoma arising in a PXA. | 21479234 | 2011 |