Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913500
rs121913500
IDH1
0.030 GeneticVariation BEFREE We therefore examined 212 diffuse astrocytomas (grade II WHO) in adults using IDH1(R132H) immunohistochemistry followed by IDH1/IDH2 sequencing and neuroimaging review. 29444314

2018
dbSNP: rs121913500
rs121913500
IDH1
0.030 GeneticVariation BEFREE Furthermore, we observed that most recurrences had a consistent IDH1 and ATRX status with their matched primary tumors and demonstrated the progressive pattern of grade II astrocytoma/oligodendroglial tumors and anaplastic oligoastrocytoma with or without IDH1-R132H. 26918938

2016
dbSNP: rs121913500
rs121913500
IDH1
0.030 GeneticVariation BEFREE We evaluated nuclear cMYC protein levels and IDH1 (R132H) by immunohistochemistry in patients with oligodendroglioma/oligoastrocytomas (n = 20), astrocytomas (grade II) (n = 19), anaplastic astrocytomas (n = 21) or glioblastomas (n = 111). 23934175

2013
dbSNP: rs118101777
rs118101777
IDH2
0.020 GeneticVariation BEFREE We therefore examined 212 diffuse astrocytomas (grade II WHO) in adults using IDH1(R132H) immunohistochemistry followed by IDH1/IDH2 sequencing and neuroimaging review. 29444314

2018
dbSNP: rs113488022
rs113488022
BRAF
0.020 GeneticVariation BEFREE However, the BRAF V600E mutation was detected only in epithelioid glioblastoma but not in low-grade diffuse astrocytoma. 26375727

2016
dbSNP: rs113488022
rs113488022
BRAF
0.020 GeneticVariation BEFREE Malignant transformation of diffuse astrocytoma to glioblastoma associated with newly developed BRAF V600E mutation. 26404554

2016
dbSNP: rs118101777
rs118101777
IDH2
0.020 GeneticVariation BEFREE Furthermore, we observed that most recurrences had a consistent IDH1 and ATRX status with their matched primary tumors and demonstrated the progressive pattern of grade II astrocytoma/oligodendroglial tumors and anaplastic oligoastrocytoma with or without IDH1-R132H. 26918938

2016
dbSNP: rs121913377
rs121913377
BRAF
0.020 GeneticVariation BEFREE However, the BRAF V600E mutation was detected only in epithelioid glioblastoma but not in low-grade diffuse astrocytoma. 26375727

2016
dbSNP: rs121913377
rs121913377
BRAF
0.020 GeneticVariation BEFREE Malignant transformation of diffuse astrocytoma to glioblastoma associated with newly developed BRAF V600E mutation. 26404554

2016
dbSNP: rs55819519
rs55819519
TP53
0.010 GeneticVariation BEFREE We evaluated nuclear cMYC protein levels and IDH1 (R132H) by immunohistochemistry in patients with oligodendroglioma/oligoastrocytomas (n = 20), astrocytomas (grade II) (n = 19), anaplastic astrocytomas (n = 21) or glioblastomas (n = 111). 23934175

2013
dbSNP: rs662
rs662
PON1
0.010 GeneticVariation BEFREE Seventy one consecutive patients with brain tumors (43 with astrocytoma grade II/III and 28 with meningioma) with ages ranging 21 to 76 years, and 220 healthy controls subjects were analyzed for the frequency of the nonsynonymous PON1 genotypes L55M rs854560 and Q192R rs662. 20723250

2010
dbSNP: rs854560
rs854560
PON1
0.010 GeneticVariation BEFREE Seventy one consecutive patients with brain tumors (43 with astrocytoma grade II/III and 28 with meningioma) with ages ranging 21 to 76 years, and 220 healthy controls subjects were analyzed for the frequency of the nonsynonymous PON1 genotypes L55M rs854560 and Q192R rs662. 20723250

2010
dbSNP: rs5498
rs5498
ICAM1 ; ICAM4
0.010 GeneticVariation BEFREE However, a specific ICAM-1 genotype (G/G, corresponding to Lys469Glu) exhibited higher frequency in grade II astrocytomas compared to controls, grade III, and grade IV astrocytomas; suggesting that this polymorphism could be involved in the development of grade II astrocytomas. 19306055

2009