RESULTS The mutant homozygous genotype in codominant model (AA versus GG, OR=2.37, 95% CI: 1.08-5.21, P=0.001) and in recessive model (AA versus GG/GA, OR=2.82, 95% CI: 1.30-6.12, P=0.005) of rs956730 were associated with an increased LDH risk in males, while rs956730 heterozygous genotype under codominant model (AG versus GG, OR=0.65, 95% CI: 0.46-0.92, P=0.001) was a protective genotype in males.