| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | BEFREE | This meta-analysis demonstrated that polymorphisms in MspI and Ile462Val of CYP1A1 were risk factors for developing cervical cancer. | 29595663 | 2018 |
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|
0.090 | GeneticVariation | BEFREE | The total analysis revealed a borderline relationship between <i>CYP1A1</i> Ile462Val polymorphism and cervic</span>al cancer risk in general population. | 29326607 | 2017 |
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|
0.090 | GeneticVariation | BEFREE | Our study suggested that the presence of 'C' allele of rs4646903 (T>C) showed no risk and 'G' allele of rs1048943 (A>G) might be a leading allele to cause increased cervical cancer susceptibility due to significant association of CYP1A1m2 gene polymorphism. | 28433806 | 2017 |
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|
0.090 | GeneticVariation | BEFREE | rs4646903 minor alleles and interaction between rs4646903 and rs1048943 were associated with increased cervical cancer risk. | 27265845 | 2016 |
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|
0.090 | GeneticVariation | BEFREE | (2) rs1048943 (CYP1A1 A4889G) showed the strongest association with cervical cancer in the allele effect model (1.83[1.57, 2.13]); in addition, rs1048943 (CYP1A1 A4889G) had a very strong association in the dominant and recessive effect model. | 25928231 | 2015 |
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|
0.090 | GeneticVariation | BEFREE | Our genetic study suggests that the CYP1A1 Ile462Val SNP may be a risk factor for cervical cancer among patients with a positive history of tobacco smoking and parity. | 24626963 | 2014 |
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|
0.090 | GeneticVariation | BEFREE | Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer in a North Indian population. | 24657182 | 2014 |
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|
0.090 | GeneticVariation | BEFREE | Further stratified analysis by cancer types revealed that the MspI polymorphism may increase the risk of lung cancer and cervical cancer whereas the Ile462Val polymorphism may contribute to a higher risk of lung cancer, leukemia, esophageal carcinoma, and prostate cancer. | 24391993 | 2013 |
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|
0.090 | GeneticVariation | BEFREE | In conclusion, this meta-analysis suggests that CYP1A1 Ile462Val polymorphism plays an important role in susceptibility to cervical cancer. | 22948778 | 2012 |