DisGeNET - a database of gene-disease associations

Cervix carcinoma, C0302592

Variant: rs11134527 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11134527

SLIT3 ; MIR218-2

0.040

GeneticVariation

BEFREE

These results indicated that rs11134527 in pri-miR-218-2 and rs531564 in pri-miR-124-1 could be associated with CIN and cervical cancer in the Chinese Han population.

29152130

2017

dbSNP:

rs11134527

SLIT3 ; MIR218-2

0.040

GeneticVariation

BEFREE

MiR-218 plays an important role in heart development in zebrafish. pri-miR-218 rs11134527 variant is associated with cervical cancer carcinogenesis.

23566829

2013

dbSNP:

rs11134527

SLIT3 ; MIR218-2

0.040

GeneticVariation

BEFREE

The pri-miR-218 rs11134527 SNP was significantly associated with the risk of cervical carcinoma in Eastern Chinese women.

23320911

2013

dbSNP:

rs11134527

SLIT3 ; MIR218-2

0.040

GeneticVariation

BEFREE

These findings indicate that pri-miR-218 rs11134527 and LAMB3 rs2566 may contribute to cervical cancer carcinogenesis, and further validations in diverse populations and functional characterizations are warranted.

20163849

2010