Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1289324472
rs1289324472
GBA
0.020 GeneticVariation BEFREE The N370S GBA mutation is the risk factor for cognitive impairment in PD patients. 25168325

2014

dbSNP: rs1289324472
rs1289324472
GBA
0.020 GeneticVariation BEFREE There were 14 GD+PD patients: all Ashkenazi Jewish; 11 males (78.6%); mean (range) age diagnosed GD 34.2 (5-62) years; 50% N370S homozygous; mild to moderate GD; 3 asplenic and only these have osteonecrosis; 5 received ERT; mean age (range) diagnosed PD was 57.8 (43-70) years; first PD sign was tremor in 9 (64.3%); cognitive dysfunction in all. 25111979

2014