rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly.
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31771052 |
2020 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The association between higher BDNF levels and cognitive impairment, mainly attention in smokers appears to be dependent on the BDNF Val66Met polymorphism.
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30659208 |
2019 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers.
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30775992 |
2019 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy.
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30382534 |
2019 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Our meta-analysis implicates Val66Met BDNF polymorphism may be associated with Parkinson's disease cognitive impairment, further well-designed studies with larger populations are required to validate these results owing to the limited research.
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31104169 |
2019 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
We examined whether BDNF Val66Met variation was associated with cognitive impairment in mTLE.
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29952080 |
2019 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Our analyses suggested the G196A (Val66Met) polymorphism was significantly associated with cog</span>nitive impairment in PD, especially in Caucasian populations.
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31365694 |
2019 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
<i>BDNF</i> gene Val66Met variation may be associated with cognitive deficits in T2DM, especially with delayed memory.
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29423073 |
2018 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Several heritability studies have reported that the Brain Derived Neurotrophic Factor (<i>BDNF</i>) Val66Met genetic polymorphism could contribute to the acceleration of cognitive decline in aging.
|
30333719 |
2018 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
These results support the hypothesis of the BDNF Val66Met polymorphism as a risk factor associated with cognitive impairment, corroborating previous findings in young and older adults.
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28099630 |
2017 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
These results suggest that the <i>BDNF</i> Val66Met polymorphism may play an important role in cognitive decline and could be considered as a target for novel AD therapeutics.
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28468845 |
2017 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
This article reviews the current literature available regarding associations between the Val66Met polymorphism, childhood trauma and cognitive dysfunction in schizophrenia.
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26603624 |
2016 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
These results suggest a role for BDNF Val66Met polymorphism on cognitive impairment in PD.
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26806863 |
2016 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism, resting-state hippocampal functional connectivity and cognitive deficits in acute late-onset depression.
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26000753 |
2015 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
This study investigated the effects of BDNF Val66Met polymorphism on functional magnetic resonance imaging (fMRI) during n-back WM tasks in healthy middle-aged adults.A total of 110 participants without subjective or objective cognitive impairment underwent BDNF genotyping.
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26496261 |
2015 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
BDNF G196A (Val66Met) polymorphism associated with cognitive impairment in Parkinson's disease.
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24394906 |
2014 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
We investigated whether a common Val66Met missense polymorphism (rs6265) of the BDNF gene is associated with individual differences in cognitive decline (marked by perceptual speed) in old age.
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24660789 |
2014 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Our findings supported the hypothesis that the BDNF Val66Met polymorphism may affect susceptibility to regional WMH volume and such genotype-by-WMH interaction effect is correlated with cognitive decline in non-demented elderly males, in which the Met allele plays a protective role.
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24275008 |
2014 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The BDNF val66met polymorphism is a potential vulnerability factor for cognitive impairment in BD.
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24862657 |
2014 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism has previously been implicated in Alzheimer's disease (AD)-related cognitive impairment.
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23769397 |
2013 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The effect of the Val66Met polymorphism on synaptic transmission and plasticity in the IL-mPFC represents a mechanism to account for this impact of SNP on affective disorders and cognitive dysfunction.
|
22396415 |
2012 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The association between decreased BDNF serum levels and cognitive impairment in schizophrenia is dependent on the BDNF Val66Met polymorphism.
|
22362486 |
2012 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
BDNF Val66Met polymorphism is associated with cognitive impairment in Italian patients with Parkinson's disease.
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19538209 |
2009 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The Met66 allele of the functional Val66Met polymorphism in the brain-derived neurotrophic factor gene confers protection against neurocognitive dysfunction in systemic lupus erythematosus.
|
16606648 |
2006 |
rs759834365
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0.100 |
GeneticVariation |
BEFREE |
These findings suggest that the functional BDNF Val66Met variant is not a major determinant of rate of cognitive decline in AD.
|
16627933 |
2006 |