Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4240384
rs4240384
LINC02240 ; LOC107986391
0.700 GeneticVariation GWASCAT Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. 29904099

2019
dbSNP: rs8008716
rs8008716
LINC02588
G 0.700 GeneticVariation GWASCAT GWAS identifies four novel eosinophilic esophagitis loci. 25407941

2014
dbSNP: rs371915
rs371915
MEAK7
0.700 GeneticVariation GWASCAT Common variants at 5q22 associate with pediatric eosinophilic esophagitis. 20208534

2010
dbSNP: rs1059513
rs1059513
NAB2 ; STAT6
0.010 GeneticVariation BEFREE Carriage of STAT6 allelic variant rs1059513 predicts PPI-REE (OR [95% CI] = 6.16 [1.44, 26.4], P = 0.028), whereas carriage of STAT6 rs324011 synergizes with CYP2C1917 to predict PPI-nonresponsive EoE (rs324011 OR [95% CI] = 5.56 [1.33, 20.72], P = 0.022; CYP2C1917 OR [95% CI] = 8.19[1.42, 50.57], P = 0.023). 31490856

2019
dbSNP: rs2075277
rs2075277
P2RX6
0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104

2014
dbSNP: rs11206830
rs11206830
PLPP3
0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104

2014
dbSNP: rs1986734
rs1986734
SHROOM3
0.700 GeneticVariation GWASCAT Common variants at 5q22 associate with pediatric eosinophilic esophagitis. 20208534

2010
dbSNP: rs167769
rs167769
STAT6
T 0.700 GeneticVariation GWASCAT GWAS identifies four novel eosinophilic esophagitis loci. 25407941

2014
dbSNP: rs324011
rs324011
STAT6
0.010 GeneticVariation BEFREE Carriage of STAT6 allelic variant rs1059513 predicts PPI-REE (OR [95% CI] = 6.16 [1.44, 26.4], P = 0.028), whereas carriage of STAT6 rs324011 synergizes with CYP2C1917 to predict PPI-nonresponsive EoE (rs324011 OR [95% CI] = 5.56 [1.33, 20.72], P = 0.022; CYP2C1917 OR [95% CI] = 8.19[1.42, 50.57], P = 0.023). 31490856

2019
dbSNP: rs3744790
rs3744790
TIMP2 ; CEP295NL
0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104

2014
dbSNP: rs3806932
rs3806932
TSLP
0.720 GeneticVariation GWASCAT Common variants at 5q22 associate with pediatric eosinophilic esophagitis. 20208534

2010
dbSNP: rs3806932
rs3806932
TSLP
0.720 GeneticVariation BEFREE We report association of EoE with variants at chromosome 5q22 encompassing TSLP and WDR36 (rs3806932, combined P = 3.19 x 10(-9)). 20208534

2010
dbSNP: rs3806932
rs3806932
TSLP
0.720 GeneticVariation BEFREE For TSLP-WDR36 region, rs3806932 (G allele protective against eosinophilic esophagitis) and rs2416257 (A allele associated with lower eosinophil counts and protective against asthma) were correlated with decreased expression of TSLP in BAL (P = 7.9 × 10(-11) and 5.4 × 10(-4) , respectively) and BEC, but not WDR36. 26119467

2015
dbSNP: rs3806933
rs3806933
TSLP
G 0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104

2014
dbSNP: rs10062929
rs10062929
TSLP
0.010 GeneticVariation BEFREE A single SNP residing in the TSLP gene reached Bonferroni linkage disequilibrium-adjusted significance but only when patients with EE were compared with allergic control subjects (rs10062929; P = 4.11 x 10(-5); odds ratio, 0.35). 20620568

2010
dbSNP: rs2416257
rs2416257
WDR36
0.010 GeneticVariation BEFREE For TSLP-WDR36 region, rs3806932 (G allele protective against eosinophilic esophagitis) and rs2416257 (A allele associated with lower eosinophil counts and protective against asthma) were correlated with decreased expression of TSLP in BAL (P = 7.9 × 10(-11) and 5.4 × 10(-4) , respectively) and BEC, but not WDR36. 26119467

2015
dbSNP: rs2898261
rs2898261
XKR6
C 0.700 GeneticVariation GWASCAT Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. 25017104

2014