The homozygous genotype of the rs3761548 variants (A/A) (related to decreased FOXP3 expression) may exert a protective role against HPV infection in women (OR<sub>Aj</sub>: 0.60; 95% CI 0.36-0.99; p = 0.049) and was an independent predictor of protection against HSIL development (OR<sub>Adj</sub>: 0.28; 95% CI 0.11-0.68; p = 0.006).