rs77724903
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1136201
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study analysing a cohort of 348 German familial breast cancer cases and 960 corresponding controls showed no significant association of either Ile655Val (OR = 1.05, 95% CI = 0.82-1.34, P = 0.728) or Ala1170Pro (OR = 0.94, 95% CI = 0.74-1.20, P = 0.632) with familial breast cancer risk.
|
15550452 |
2005 |
rs1058808
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study analysing a cohort of 348 German familial breast cancer cases and 960 corresponding controls showed no significant association of either Ile655Val (OR = 1.05, 95% CI = 0.82-1.34, P = 0.728) or Ala1170Pro (OR = 0.94, 95% CI = 0.74-1.20, P = 0.632) with familial breast cancer risk.
|
15550452 |
2005 |
rs28363284
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A RAD51D variant, E233G, was initially identified as a potential susceptibility allele in high-risk, site-specific, familial breast cancer.
|
19347880 |
2009 |
rs34301344
|
|
|
0.040 |
GeneticVariation |
BEFREE |
ARLTS1 is a tumor suppressor gene initially described as a low-penetrance cancer gene: a truncated Trp149Stop (MUT) polymorphism is associated with general familial cancer aggregation and, particularly, high-risk familial breast cancer.
|
17079447 |
2006 |
rs755100942
|
|
|
0.040 |
GeneticVariation |
BEFREE |
ARLTS1 is a tumor suppressor gene initially described as a low-penetrance cancer gene: a truncated Trp149Stop (MUT) polymorphism is associated with general familial cancer aggregation and, particularly, high-risk familial breast cancer.
|
17079447 |
2006 |
rs13010627
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant.
|
16251207 |
2006 |
rs1045485
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant.
|
16251207 |
2006 |
rs3803185
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Both Cys148Arg and Trp149Stop were associated with an increased risk of familial or high-risk familial breast cancer, respectively.
|
16646072 |
2006 |
rs34301344
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Both Cys148Arg and Trp149Stop were associated with an increased risk of familial or high-risk familial breast cancer, respectively.
|
16646072 |
2006 |
rs755100942
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Both Cys148Arg and Trp149Stop were associated with an increased risk of familial or high-risk familial breast cancer, respectively.
|
16646072 |
2006 |
rs121917739
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Few studies have investigated the role of coding region variation in the RAD51 gene in familial breast cancer, with only one coding region variant--exon 6 c.449G>A (p.R150Q)--reported to date.
|
16762046 |
2006 |
rs1346044
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotyping analyses, performed on 816 BRCA1/2 mutation-negative German familial breast cancer patients and 1012 German controls, revealed a significant association of the WRN Cys1367Arg polymorphism with familial breast cancer (OR = 1.28, 95% CI 1.06-1.54) and high-risk familial breast cancer (OR = 1.32, 95% CI 1.06-1.65).
|
16501249 |
2006 |
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GSTP1 Ile105Val polymorphism was associated neither with sporadic nor familial breast cancer susceptibility (P value > 0.05).
|
18080216 |
2008 |
rs4645959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we analysed the influence of the rare c-MYC Asn11Ser polymorphism on familial breast cancer risk by performing a case-control study with a Polish (cases n = 349; controls n = 441) and a German (cases n = 356; controls n = 655) study population.
|
15929079 |
2005 |
rs34434221
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we analysed the potential impact of four polymorphic non-conservative amino acid exchanges (Arg494Trp, Lys526Gln, Asn1086Asp and Gly2461Ser) in AKAP13 on familial breast cancer.
|
16234258 |
2006 |
rs886039958
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we analysed the potential impact of four polymorphic non-conservative amino acid exchanges (Arg494Trp, Lys526Gln, Asn1086Asp and Gly2461Ser) in AKAP13 on familial breast cancer.
|
16234258 |
2006 |
rs4843075
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we analysed the potential impact of four polymorphic non-conservative amino acid exchanges (Arg494Trp, Lys526Gln, Asn1086Asp and Gly2461Ser) in AKAP13 on familial breast cancer.
|
16234258 |
2006 |
rs530464947
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we analysed the potential impact of four polymorphic non-conservative amino acid exchanges (Arg494Trp, Lys526Gln, Asn1086Asp and Gly2461Ser) in AKAP13 on familial breast cancer.
|
16234258 |
2006 |
rs758898660
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we analysed the potential impact of four polymorphic non-conservative amino acid exchanges (Arg494Trp, Lys526Gln, Asn1086Asp and Gly2461Ser) in AKAP13 on familial breast cancer.
|
16234258 |
2006 |
rs2241268
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we analysed the potential impact of four polymorphic non-conservative amino acid exchanges (Arg494Trp, Lys526Gln, Asn1086Asp and Gly2461Ser) in AKAP13 on familial breast cancer.
|
16234258 |
2006 |
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we investigated the possible role of the Ins16bp and Arg72Pro polymorphisms and their haplotypes as low-penetrance alleles in familial breast cancer.
|
18640791 |
2008 |
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we investigated the possible role of the Ins16bp and Arg72Pro polymorphisms and their haplotypes as low-penetrance alleles in familial breast cancer.
|
18640791 |
2008 |
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we investigated the possible role of the Ins16bp and Arg72Pro polymorphisms and their haplotypes as low-penetrance alleles in familial breast cancer.
|
18640791 |
2008 |
rs144567652
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patients.
|
28702895 |
2017 |