Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs34301344
rs34301344
0.040 GeneticVariation BEFREE ARLTS1 is a tumor suppressor gene initially described as a low-penetrance cancer gene: a truncated Trp149Stop (MUT) polymorphism is associated with general familial cancer aggregation and, particularly, high-risk familial breast cancer. 17079447

2006

dbSNP: rs34301344
rs34301344
0.040 GeneticVariation BEFREE On the basis of the small number of 46 cases, we additionally showed an association between the Trp149Stop mutation and an increased risk of bilateral BC (OR=4.11, 95% CI=1.27-13.31, p=0.011). 16353159

2006

dbSNP: rs34301344
rs34301344
0.040 GeneticVariation BEFREE The Cys148Arg and Trp149Stop variants in the tumour suppressor gene ARLTS1 predispose to familial breast cancer, suggesting that these variants might also contribute to colorectal carcinogenesis. 16488076

2006

dbSNP: rs34301344
rs34301344
0.040 GeneticVariation BEFREE Both Cys148Arg and Trp149Stop were associated with an increased risk of familial or high-risk familial breast cancer, respectively. 16646072

2006