rs6624304
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Swedish men with the variant AR haplotype H2, tagged by rs6624304, have significantly lower risk of PCa compared to those with the more common variant.
|
28176139 |
2017 |
rs6152
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the relationships between male androgenetic alopecia, androgen receptor (AR) gene polymorphism (SNP rs6152) and clinical characteristics of BPH and prostate cancer.
|
24665929 |
2015 |
rs777787518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MDA prostate cancer 118a and MDA prostate cancer 118b cells carry a mutated β-catenin at codon 32 (D32G).
|
22298898 |
2012 |
rs139756052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additional studies will be required to define the frequency and contribution of the AR (A1675T) allele to early-onset and/or familial PCa in African Americans.
|
20173765 |
2010 |
rs968098233
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the vast majority of AR mutations appeared capable of increased activation in response to ART-27, an AR mutation identified in prostate cancer (AR P340L) and AIS (AR E2K) show reduced transcriptional responses to ART-27, whereas their response to the p160 class of coactivators was not diminished.
|
15919721 |
2005 |
rs1057519864
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Using multiple prostate cancer cell lines, we showed that catalytic Topo II inhibitors, ICRF187 and ICRF193 inhibited transcription activities of the wild-type AR, mutant ARs (F876L and W741C) and the AR-V7 splice variant.
|
26009876 |
2015 |
rs1057519864
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A missense mutation in the ligand-binding domain of the androgen receptor F876L confers resistance to the second-generation antiandrogens enzalutamide and ARN-509 in preclinical models of AR function and prostate cancer and is detected in plasma DNA from ARN-509-treated patients with progressive disease.
|
23779130 |
2013 |
rs976306779
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, the results confirm the oncogenic nature of S100P in prostate cancer and suggest that the protein may directly confer resistance to chemotherapy.
|
18452169 |
2008 |
rs976306779
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A link between elevated IL6 and up-regulated S100P in androgen-refractory and metastatic PCa is postulated.
|
15474988 |
2005 |
rs1034866440
|
|
|
0.040 |
GeneticVariation |
BEFREE |
However, no clear consensus has been reached on the association between the SRD5A2 V89L, A49T and TA repeat polymorphisms and prostate cancer (PCa) risk.
|
21177315 |
2011 |
rs137852569
|
|
|
0.040 |
GeneticVariation |
BEFREE |
However, no clear consensus has been reached on the association between the SRD5A2 V89L, A49T and TA repeat polymorphisms and prostate cancer (PCa) risk.
|
21177315 |
2011 |
rs1034866440
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The SRD5A2 polymorphisms A49T, V89L and R227Q, the androgen receptor CAG and GGN repeats and sex hormone status was investigated in men with prostate cancer (CaP) (n=89), benign prostate hyperplasia (n=45) and healthy military conscripts (n=223).
|
16039774 |
2005 |
rs137852569
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The SRD5A2 polymorphisms A49T, V89L and R227Q, the androgen receptor CAG and GGN repeats and sex hormone status was investigated in men with prostate cancer (CaP) (n=89), benign prostate hyperplasia (n=45) and healthy military conscripts (n=223).
|
16039774 |
2005 |
rs1034866440
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Cytosine-adenine-guanine repeat length of the androgen receptor gene and the A49T and V89L polymorphisms of the 5 alpha-reductase (SRD5A2) gene have been associated with prostate cancer.
|
12210487 |
2002 |
rs1034866440
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of the present study was to evaluate the distribution of polymorphisms for the androgen receptor (AR) (CAG, StuI, GGN), SRD5A2 (Ala49Thr, Val89Leu) and CYP17 (MspA1) genes that are considered to be relevant for risk of prostate cancer.
|
11847524 |
2002 |
rs137852569
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The aim of the present study was to evaluate the distribution of polymorphisms for the androgen receptor (AR) (CAG, StuI, GGN), SRD5A2 (Ala49Thr, Val89Leu) and CYP17 (MspA1) genes that are considered to be relevant for risk of prostate cancer.
|
11847524 |
2002 |
rs137852569
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Cytosine-adenine-guanine repeat length of the androgen receptor gene and the A49T and V89L polymorphisms of the 5 alpha-reductase (SRD5A2) gene have been associated with prostate cancer.
|
12210487 |
2002 |
rs1340026226
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs137852567
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs137852580
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs137852582
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs137852583
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs137852584
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs137852591
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs138454018
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|