Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs864622007
rs864622007
AR
A 0.830 GeneticVariation CLINVAR

dbSNP: rs864622007
rs864622007
AR
0.830 GeneticVariation UNIPROT

dbSNP: rs137852564
rs137852564
AR
A 0.800 CausalMutation CLINVAR

dbSNP: rs137852564
rs137852564
AR
0.800 GeneticVariation UNIPROT

dbSNP: rs137852578
rs137852578
AR
0.800 GeneticVariation UNIPROT

dbSNP: rs137852593
rs137852593
AR
0.740 GeneticVariation UNIPROT

dbSNP: rs137852581
rs137852581
AR
0.720 GeneticVariation UNIPROT

dbSNP: rs137852571
rs137852571
AR
0.710 GeneticVariation UNIPROT

dbSNP: rs1340026226
rs1340026226
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852567
rs137852567
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852580
rs137852580
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852582
rs137852582
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852583
rs137852583
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852584
rs137852584
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852591
rs137852591
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs138454018
rs138454018
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs78686797
rs78686797
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs868669253
rs868669253
AR
0.700 GeneticVariation UNIPROT

dbSNP: rs137852593
rs137852593
AR
0.740 GeneticVariation BEFREE R726L androgen receptor mutation is uncommon in prostate cancer families in the united states. 12539229

2003

dbSNP: rs137852593
rs137852593
AR
0.740 GeneticVariation BEFREE R726L substitution in the hormone binding region of androgen receptor was found in 1 prostate cancer family but no previously uncharacterized germline mutations were detected. 14665948

2004

dbSNP: rs137852578
rs137852578
AR
0.800 GeneticVariation BEFREE A prostate cancer mouse model was generated by selectively mutating the AR threonine 877 into alanine in prostatic epithelial cells through Cre-ERT2-mediated targeted somatic mutagenesis. 21383160

2011

dbSNP: rs976306779
rs976306779
AR
0.020 GeneticVariation BEFREE A link between elevated IL6 and up-regulated S100P in androgen-refractory and metastatic PCa is postulated. 15474988

2005

dbSNP: rs1057519864
rs1057519864
AR
0.020 GeneticVariation BEFREE A missense mutation in the ligand-binding domain of the androgen receptor F876L confers resistance to the second-generation antiandrogens enzalutamide and ARN-509 in preclinical models of AR function and prostate cancer and is detected in plasma DNA from ARN-509-treated patients with progressive disease. 23779130

2013

dbSNP: rs137852578
rs137852578
AR
0.800 GeneticVariation BEFREE A total of four human prostate cancer cell models were examined: LNCaP (T877A mutant AR), 22Rv1 (H874Y mutant AR), LAPC4 (wild-type AR), and VCaP (wild-type AR). 23813737

2013

dbSNP: rs139756052
rs139756052
AR
0.010 GeneticVariation BEFREE Additional studies will be required to define the frequency and contribution of the AR (A1675T) allele to early-onset and/or familial PCa in African Americans. 20173765

2010