Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs41341748
rs41341748
MSR1
0.060 GeneticVariation BEFREE We examined polymorphisms within ELAC2 (S217L, A541T, E622V), MSR1 (P275A, R293X, aIVS5-59c), and RNASEL (E265X, R462Q, D541E) in 150 European-Americans with metastatic prostate cancer and 170 prostate cancer-free controls using pyrosequencing assays. 16114055

2006
dbSNP: rs41341748
rs41341748
MSR1
0.060 GeneticVariation BEFREE Of note, carriers of R293X were equally frequent in 367 sporadic prostate cancer cases (1.9%) and in 197 controls (2.0%). 16287155

2006
dbSNP: rs41341748
rs41341748
MSR1
0.060 GeneticVariation BEFREE Several variants were significantly or marginally significantly associated with sporadic, not hereditary PCa risk, including R293X in white men (random effect OR = 1.34, P = 0.09) and D174Y in black men (random effect OR = 2.41, P = 0.04). 16425212

2006
dbSNP: rs41341748
rs41341748
MSR1
0.060 GeneticVariation BEFREE Meta-analyses revealed significant associations of prostate cancer with MSR1 IVS7delTTA, -14,742 A>G, and Arg293X in European Americans; Asp174Tyr in African Americans; RNASEL Arg462Gln in European American's overall and in family history-negative disease; and Glu265X in family history-positive European Americans. 15824169

2005
dbSNP: rs41341748
rs41341748
MSR1
0.060 GeneticVariation BEFREE Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer. 15734964

2005
dbSNP: rs41341748
rs41341748
MSR1
0.060 GeneticVariation BEFREE Our results suggest that mutations in MSR1 gene might play a role in prostate cancer susceptibility, particularly the R293X mutation. 15042613

2004