|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis showed evidence that ELAC2 Ser217Leu and Ala541Thr polymorphisms were associated with prostate cancer risk, and might be low-penetrance susceptibility markers of prostate cancer.
|
20231859 |
2010 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
No individual SNP (including Ser217Leu) was associated with the risk of prostate cancer.
|
18375959 |
2008 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
To determine the contribution of two HPC2/ELAC2 missense variants (Ser217Leu and Ala541Thr) to the risk of developing prostate cancer, we conducted a population-based case-control study of middle-aged men (40-64 years).
|
14504198 |
2003 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Two HPC2 gene missense variants, Ser217Leu (Leu217) and Ala541Thr (Thr541) have been associated with incident prostate cancer cases in some studies, but not in others.
|
14625808 |
2003 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Ser217Leu polymorphism of the HPC2/ELAC2 gene associated with prostatic cancer risk in Japanese men.
|
12949798 |
2003 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The ELAC2 gene has been proposed to be a prostate cancer susceptibility gene and is being referred to as HPC2, in part because three case-control studies suggested that two common polymorphisms (Ser217Leu and Ala541Thr) are associated with risk.
|
12783937 |
2003 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The candidate prostate cancer susceptibility gene HPC2/ELAC2 has two common coding polymorphisms: (Ser-->Leu 217) and (Ala-->Thr 541).
|
12373607 |
2002 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The recently identified prostate cancer susceptibility gene ELAC2 ( HPC2) harbors two common missense variants, a serine to leucine substitution at residue 217 (Leu217) and an alanine to threonine substitution at residue 541 (Thr541).
|
12522685 |
2002 |
|
rs4792311
|
|
|
0.090 |
GeneticVariation |
BEFREE |
To test the hypothesis that variation in the putative prostate cancer susceptibility gene ELAC2 contributes to the elevated risk of prostate cancer in Afro-Caribbean males from Tobago, we genotyped the S217L and A514T polymorphisms, previously reported to be associated with prostate cancer risk in a large sample of cases and controls.
|
12384782 |
2002 |