Gene: BRCA1 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799950
rs1799950
BRCA1
0.020 GeneticVariation BEFREE Six markers associated with early-onset prostate cancer [rs2171492 (7q32), rs6983561 (8q24), rs10993994 (10q11), rs4430796 (17q12), rs1799950 (17q21), and rs266849 (19q13)] were genotyped. 22144497

2012
dbSNP: rs1799950
rs1799950
BRCA1
0.020 GeneticVariation BEFREE In addition, Genotype-Identity-by-Descent Sharing Test results suggest that Gln(356)Arg accounts (in part) for our prior evidence of prostate cancer linkage to chromosome 17q21 (P = 0.022). 17585057

2007
dbSNP: rs886040226
rs886040226
BRCA1
0.010 GeneticVariation BEFREE To our knowledge, we are the first to report the germline BRCA2 mutation c.4211C>G (p.Ser1404Ter) in prostate cancer. 29580149

2018
dbSNP: rs8176305
rs8176305
BRCA1
0.010 GeneticVariation BEFREE We found that two SNPs, rs4473733 (HR: 0.65; 95% CI 0.42-0.99) and rs8176305 (HR: 2.03; 95% CI 1.33-3.10), were associated with lethal prostate cancer in men receiving RT. 26926928

2016
dbSNP: rs80357382
rs80357382
BRCA1
0.010 GeneticVariation BEFREE Our conclusive trial demonstrates the lack of association between Galician splicing mutation c.211A>G in the BRCA1 gene and prostate cancer risk. 21520156

2011
dbSNP: rs28897672
rs28897672
BRCA1
0.010 GeneticVariation BEFREE To establish whether or not inherited variation in BRCA1 influences prostate cancer risk we genotyped 1793 men with prostate cancer in Poland and 4570 controls for three founder mutations (C61G, 4153delA and 5382insC). 18090912

2008
dbSNP: rs80357796
rs80357796
BRCA1
0.010 GeneticVariation BEFREE In addition, Genotype-Identity-by-Descent Sharing Test results suggest that Gln(356)Arg accounts (in part) for our prior evidence of prostate cancer linkage to chromosome 17q21 (P = 0.022). 17585057

2007