|
rs1260326
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Additionally, our results suggest Asian-specific, liver biopsy-specific, adult-specific and pediatric-specific associations between the rs1260326 and NAFLD.
|
30646922 |
2019 |
|
rs1260326
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Among the eleven genotyped SNPs, the genetic variants in TM6SF2 rs58542926 (OR = 4.13, p = 0.002), GCKR rs1260326 (OR = 1.53, p = 0.003), PNPLA3 rs738409 (OR = 1.58, p = 0.004) and ELOVL2 rs2236212 (OR = 1.34, p = 0.047) were significantly associated with a higher risk of NAFLD.
|
31255630 |
2019 |
|
rs1260326
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Our results show that GCKR rs1260326 T-allele is associated with better response of NAFLD patients to nutritional treatment regarding fasting blood glucose, but not oxLDL levels.
|
28695325 |
2018 |
|
rs1260326
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Among individual variants, rs1260326 in GCKR and rs641738 in MBOAT7 (recessive), rs58542926 in TM6SF2 and rs738409 in PNPLA3 (dominant) emerged as associated to NAFLD, with PNPLA3 rs738409 being the strongest predictor (OR 3.12, 95% CI, 1.8-5.5, P < 0.001).
|
29487372 |
2018 |
|
rs1260326
|
|
T |
0.760 |
GeneticVariation |
GWASCAT |
Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.
|
29385134 |
2018 |
|
rs1260326
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Here we show that adiposity significantly amplifies the effect of three sequence variants (encoding PNPLA3 p.I148M, TM6SF2 p.E167K, and GCKR p.P446L) associated with nonalcoholic fatty liver disease (NAFLD).
|
28436986 |
2017 |
|
rs1260326
|
|
|
0.760 |
GeneticVariation |
BEFREE |
This study suggests that risk allele T of the GCKR rs780094 and rs1260326 is associated with predisposition to NAFLD and NASH with significant fibrosis.
|
23800943 |
2014 |