| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.760 | GeneticVariation | BEFREE | Our results revealed a possible genetic association between GDF5 and KOA, and the TT genotype of rs143383 increased the risk of KOA in Chinese Han population. | 30777926 | 2019 |
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0.760 | GeneticVariation | GWASCAT | Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. | 30664745 | 2019 |
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0.760 | GeneticVariation | BEFREE | The TT genotype of the SNP rs143383 increases the susceptibility to KOA in the population of northern Mexico, according to the recessive segregation model. | 30044130 | 2018 |
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|
T | 0.760 | GeneticVariation | GWASCAT | Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. | 30374069 | 2018 |
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0.760 | GeneticVariation | BEFREE | This data suggest that the differential methylation of the +37 CpG site between osteoarthritic hip and knee cartilage may be responsible for the knee-specific effect of rs143383 on OA susceptibility. | 24861163 | 2014 |
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|
0.760 | GeneticVariation | BEFREE | Association between GDF5 rs143383 polymorphism and knee osteoarthritis: an updated meta-analysis based on 23,995 subjects. | 25467786 | 2014 |
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|
0.760 | GeneticVariation | BEFREE | Two thousand four hundred and sixty-two subjects aged 50 years and older were assessed for OA at the knee, were genotyped with two SNPs (GDF5; rs143383 and ADAM12; rs3740199). | 22284607 | 2012 |
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|
0.760 | GeneticVariation | BEFREE | That has proven to be the case for the GDF5 polymorphism rs143383, a risk factor for knee osteoarthritis and several other common conditions, including lumbar-disc degeneration and developmental dysplasia of the hip. | 21542882 | 2011 |