DisGeNET - a database of gene-disease associations

Serum LDL cholesterol measurement, C0428474

Variant: rs3846662 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs3846662

HMGCR

0.700

GeneticVariation

GWASDB

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

23100282

2013

dbSNP:

rs3846662

HMGCR

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs3846662

HMGCR

0.700

GeneticVariation

GWASDB

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

19060911

2009