Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs429358
rs429358
0.030 GeneticVariation BEFREE There was no interaction between rs9331896 in CLU and rs429358 (defining the ɛ4 allele) in APOE in predicting Alzheimer's disease or all dementia (P = 0.39 and P = 0.21). 29534716

2018

dbSNP: rs429358
rs429358
0.030 GeneticVariation BEFREE When adjusted for CSF Aß42, the association of rs429358 with de</span>mentia</span> is greatly reduced but remains significant indicating that APOE polymorphism influences disease by additional mechanisms distinct from Aß42 metabolism. 20847432

2010

dbSNP: rs429358
rs429358
0.030 GeneticVariation BEFREE The apo E4 (Arg112-Cys) polymorphism has been associated with dementia and hypercholesterolemia. 11257253

2001