Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12083537
rs12083537
0.010 GeneticVariation BEFREE Our results indicate that rs12083537 and rs8192284 in the IL6R gene might be related to the risk of IS in MetS patients. 31836512

2020

dbSNP: rs2010963
rs2010963
0.010 GeneticVariation BEFREE Interaction between Vascular Endothelial Growth Factor-A (rs2010963) Gene Polymorphisms and Dietary Diversity Score on Cardiovascular Risk Factors in Patients with Metabolic Syndrome. 31786572

2020

dbSNP: rs10033652
rs10033652
0.010 GeneticVariation BEFREE A known coronary artery disease risk locus rs2292954 in <i>SPG7</i> associated with systolic WCE (discovery <i>p</i> value = 2.2 × 10<sup>-6</sup>, replication <i>p</i> value = 0.03 in Finn-Home, meta-analysis <i>p</i> value 2.6 × 10<sup>-4</sup>), and rs10033652 in <i>RASGEF1B</i> with diastolic WCE (discovery <i>p</i> value = 4.9 × 10<sup>-6</sup>, replication <i>p</i> value = 0.04 in DILGOM, meta-analysis <i>p</i> value = 5.0 × 10<sup>-3</sup>). 31044621

2019

dbSNP: rs10845640
rs10845640
0.010 GeneticVariation BEFREE Four genetic variants (APOA5_rs651821, EFCAB4B_rs4766165, ZNF259_rs2160669 and APOBEC1_rs10845640) were selected because they increased MetS risk after adjusting for covariates. 31544728

2019

dbSNP: rs1800796
rs1800796
0.010 GeneticVariation BEFREE We demonstrate an association between the rs1800796 genetic variant of the IL-6 gene with components of MetS including BMI, and HDL-cholesterol, but not the MetS itself. 30989422

2019

dbSNP: rs2160669
rs2160669
0.010 GeneticVariation BEFREE Four genetic variants (APOA5_rs651821, EFCAB4B_rs4766165, ZNF259_rs2160669 and APOBEC1_rs10845640) were selected because they increased MetS risk after adjusting for covariates. 31544728

2019

dbSNP: rs2292954
rs2292954
0.010 GeneticVariation BEFREE A known coronary artery disease risk locus rs2292954 in <i>SPG7</i> associated with systolic WCE (discovery <i>p</i> value = 2.2 × 10<sup>-6</sup>, replication <i>p</i> value = 0.03 in Finn-Home, meta-analysis <i>p</i> value 2.6 × 10<sup>-4</sup>), and rs10033652 in <i>RASGEF1B</i> with diastolic WCE (discovery <i>p</i> value = 4.9 × 10<sup>-6</sup>, replication <i>p</i> value = 0.04 in DILGOM, meta-analysis <i>p</i> value = 5.0 × 10<sup>-3</sup>). 31044621

2019

dbSNP: rs2430561
rs2430561
0.010 GeneticVariation BEFREE Searching for the Role of the <i>IFNγ</i> rs2430561 Polymorphism in Inducible Inflammation: Contribution to Metabolic Syndrome in 45 to 60-Year-Old Women. 30862026

2019

dbSNP: rs2845573
rs2845573
0.010 GeneticVariation BEFREE Korean carriers of the FADS1 rs174547 and FADS2 rs2845573 minor alleles have a greater susceptibility to MetS and moderate fat intake protected against the risk of MetS in carriers of the FADS1 major alleles. 29779171

2019

dbSNP: rs28665122
rs28665122
0.010 GeneticVariation BEFREE In summary, the results of this study does not indicate significant differences in the SEPP1 (rs7579, rs3877899) and SEPS1 (rs4965373, rs28665122) genotypes between MetS and non-MetS subjects. 31542866

2019

dbSNP: rs3816117
rs3816117
0.010 GeneticVariation BEFREE We discovered two variants within/near the <i>CETP</i> gene-rs1800775 and rs3816117-associated with MetS at genome-wide significance level during replication phase in Indians. 31366177

2019

dbSNP: rs3877899
rs3877899
0.010 GeneticVariation BEFREE The mean of SePP in MetS subjects with SEPP1 (rs3877899) GG genotype is significantly lower than the non-MetS g</span>roup (40.73 ± 8.44 vs.83.91 ± 21.33, P = 0.002). 31542866

2019

dbSNP: rs45487298
rs45487298
0.010 GeneticVariation BEFREE The relationship of <i>HSD11B1</i> rs45487298 and <i>H6PD</i> rs6688832 polymorphisms with obesity and MetS was studied. 31558916

2019

dbSNP: rs4880
rs4880
0.010 GeneticVariation BEFREE Thus, we investigated the relationship between MnSOD Ala16Val SNP with epilepsy and its influence on MetS, inflammation, apoptosis and DNA damage parameters. 31212050

2019

dbSNP: rs4965373
rs4965373
0.010 GeneticVariation BEFREE The mean of SelS in MetS subjects with SEPS1 (rs4965373) GG genotype is significantly lower than the non-MetS group (4496.99 ± 3688.5 vs. 6148.6 ± 1127.0, P = 0.009). 31542866

2019

dbSNP: rs641738
rs641738
0.010 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs750359414
rs750359414
0.010 GeneticVariation BEFREE These findings propose that the RETN +62G>A polymorphism has a great impact on the circulating resistin concentrations, and that resistin levels are strongly related to MS. 31820685

2019

dbSNP: rs7579
rs7579
0.010 GeneticVariation BEFREE In summary, the results of this study does not indicate significant differences in the SEPP1 (rs7579, rs3877899) and SEPS1 (rs4965373, rs28665122) genotypes between MetS and non-MetS subjects. 31542866

2019

dbSNP: rs763000109
rs763000109
TNF
0.010 GeneticVariation BEFREE Thus, we investigated the relationship between MnSOD Ala16Val SNP with epilepsy and its influence on MetS, inflammation, apoptosis and DNA damage parameters. 31212050

2019

dbSNP: rs11063069
rs11063069
0.010 GeneticVariation BEFREE No significant interaction was observed in this study between nutrients (macronutrients, zinc, magnesium and iron) and CCND2 rs11063069 in relation to MetS or its components in this study. 29764627

2018

dbSNP: rs11773845
rs11773845
0.010 GeneticVariation BEFREE The CAV1 variation rs11773845 was found to be consistently associated with high serum triglycerides and the metabolic syndrome. 29762069

2018

dbSNP: rs121917821
rs121917821
0.010 GeneticVariation BEFREE The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS. 30381540

2018

dbSNP: rs1259867035
rs1259867035
0.010 GeneticVariation BEFREE The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS. 30381540

2018

dbSNP: rs12836771
rs12836771
0.010 GeneticVariation BEFREE We investigated whether HTR2C:rs518147 (-697G/C), rs12836771 (A/G), LEP: rs7799039 (-2548G/A) and LEPR:rs1137101 (668A/G) are related to MS in psychotic disorder patients treated with atypical antipsychotics. 29441581

2018

dbSNP: rs1289324472
rs1289324472
GBA
0.010 GeneticVariation BEFREE In the subgroup of 29 patients who were on stable ERT for at least 24 months, further to splenectomy, GD severity and non-N370S GBA1 genotypes, also diastolic blood pressure, BMI and the number of metabolic syndrome (MetS) components emerged as factors significantly associated with significant fibrosis. 30115580

2018