Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs266729
rs266729
0.060 GeneticVariation BEFREE <i>Conclusions</i>: Our findings show that APN rs266729 G/C polymorphism is associated with lower APN levels in CRC patients, indicating that decreased circulating levels of APN may be a determinant risk factor for CRC in MetS patients. 28529612

2017

dbSNP: rs266729
rs266729
0.060 GeneticVariation BEFREE <i>Results</i>: We found that CRC patients (N=75) with genotype rs266729G/C or carriers of G allele were associated with a significantly increased risk of MetS development (OR =2.9) compared to those with CC genotype (N=30). 28529612

2017

dbSNP: rs711752
rs711752
0.010 GeneticVariation BEFREE (2) rs1800775, rs3764261, rs12149545, rs711752, and rs708272 polymorphisms were significantly related to the risk of MS (all <i>p</i> < 0.05). 28629169

2017

dbSNP: rs708272
rs708272
0.030 GeneticVariation BEFREE (2) rs1800775, rs3764261, rs12149545, rs711752, and rs708272 polymorphisms were significantly related to the risk of MS (all <i>p</i> < 0.05). 28629169

2017

dbSNP: rs1800775
rs1800775
0.020 GeneticVariation BEFREE (3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05). 28629169

2017

dbSNP: rs3764261
rs3764261
0.830 GeneticVariation BEFREE (3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05). 28629169

2017

dbSNP: rs12149545
rs12149545
0.010 GeneticVariation BEFREE (3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05). 28629169

2017

dbSNP: rs5186
rs5186
0.030 GeneticVariation BEFREE Metabolic syndrome trait associations were strongest for the 3' block generally and for the C allele of rs5186:A>C specifically. 17211857

2007

dbSNP: rs397507444
rs397507444
0.040 GeneticVariation BEFREE Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants. 17976958

2008

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants. 17976958

2008

dbSNP: rs1799883
rs1799883
0.080 GeneticVariation BEFREE Metabolic syndrome and ALA54THR polymorphism of fatty acid-binding protein 2 in obese patients. 20723947

2011

dbSNP: rs17173608
rs17173608
0.020 GeneticVariation BEFREE Metabolic syndrome in Egyptian females is associated with the minor allele of chemerin rs17173608 polymorphism, whereas the minor allele of vaspin rs2236242 polymorphism plays a protective role against metabolic syndrome. 26472663

2016

dbSNP: rs2236242
rs2236242
0.020 GeneticVariation BEFREE Metabolic syndrome in Egyptian females is associated with the minor allele of chemerin rs17173608 polymorphism, whereas the minor allele of vaspin rs2236242 polymorphism plays a protective role against metabolic syndrome. 26472663

2016

dbSNP: rs738409
rs738409
0.100 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs58542926
rs58542926
0.030 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs641738
rs641738
0.010 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs3856806
rs3856806
0.060 GeneticVariation BEFREE C1431T, but not Pro12Ala polymorphisms, are associated with MS in a Chinese population. 19237017

2009

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Pro12Ala polymorphism of the peroxisome proliferatoractivated receptor-gamma gene is associated with metabolic syndrome and surrogate measures of insulin resistance in healthy men: interaction with smoking status. 19745552

2009

dbSNP: rs1801278
rs1801278
0.030 GeneticVariation BEFREE rs1801278 GA carriers had lower risk of MS, especially among smokers. 21645940

2011

dbSNP: rs7849191
rs7849191
0.010 GeneticVariation BEFREE rs7849191 and rs3780378 were both associated with reduced risk of MS [p = 0.005; OR (95%CI) = 0.52 (0.33-0.80) and p = 0.006; OR (95% CI) = 0.59 (0.40-0.86) respectively, assuming a dominant model]. rs3780378 T allele was associated with triglyceridemia values under 150 mg/dl [p = 0.007; OR (95%CI) = 0.610 (0.429-0.868)] and TT carriers showed lower triglycerides (p = 0.017), triglycerides/HDL-C ratio (p = 0.022) and lipid accumulation product (p = 0.007) compared to allele C carriers. 22185674

2011

dbSNP: rs16139
rs16139
0.010 GeneticVariation BEFREE Leu7Pro polymorphism is associated with the Met</span>S in patients with CAD. 22308535

2013

dbSNP: rs4994
rs4994
0.100 GeneticVariation BEFREE Trp64Arg polymorphism of the ADRB3 gene may affect VF accumulation and be associated with MS, a cluster of conditions involving aggravated lipid metabolism and higher blood pressure, in Japanese children. 23282015

2013

dbSNP: rs6259
rs6259
0.010 GeneticVariation BEFREE rs6259 and rs3760213 SNPs are associated with the risk of MetS and lower serum SHBG level in Chinese Han males. 24671943

2014

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention. 25432492

2014

dbSNP: rs757081
rs757081
0.010 GeneticVariation BEFREE 1012C>G polymorphism of NUCB2 is correlated with a reduced risk of developing MetS in a Chinese Han population. 26624852

2016