Gene: HSD11B1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12086634
rs12086634
HSD11B1 ; HSD11B1-AS1
0.040 GeneticVariation BEFREE The results of our study indicated that the HSD11B1 rs12086634 is associated with both T2D and metS, but HSD11B1 rs846910 is associated with only T2D in South Indian population. 28750217

2017
dbSNP: rs12086634
rs12086634
HSD11B1 ; HSD11B1-AS1
0.040 GeneticVariation BEFREE We conclude that in a South Indian population, a polymorphism of the HSD11B1 gene containing the single-nucleotide polymorphism (SNP) rs12086634 T→G confers increased risk of metabolic syndrome. 23869418

2013
dbSNP: rs12086634
rs12086634
HSD11B1 ; HSD11B1-AS1
0.040 GeneticVariation BEFREE HSD11B1 polymorphisms (rs12086634 and rs1000283) were associated with metabolic syndrome among type 2 diabetic subjects and an H6PD polymorphism (rs17368528) was a risk factor for metabolic syndrome in nondiabetic subjects. 21869537

2011
dbSNP: rs12086634
rs12086634
HSD11B1 ; HSD11B1-AS1
0.040 GeneticVariation BEFREE We conclude that, in a population of Southern European Caucasian women with and without PCOS, alleles of HSD11B1 containing the two SNPs rs846910 A and rs12086634 T confer increased 11β-HSD1 expression and activity, which associates with the metabolic syndrome. 21622477

2011
dbSNP: rs846910
rs846910
HSD11B1 ; HSD11B1-AS1
0.020 GeneticVariation BEFREE The results of our study indicated that the HSD11B1 rs12086634 is associated with both T2D and metS, but HSD11B1 rs846910 is associated with only T2D in South Indian population. 28750217

2017
dbSNP: rs846910
rs846910
HSD11B1 ; HSD11B1-AS1
0.020 GeneticVariation BEFREE We conclude that, in a population of Southern European Caucasian women with and without PCOS, alleles of HSD11B1 containing the two SNPs rs846910 A and rs12086634 T confer increased 11β-HSD1 expression and activity, which associates with the metabolic syndrome. 21622477

2011
dbSNP: rs45487298
rs45487298
HSD11B1 ; HSD11B1-AS1
0.010 GeneticVariation BEFREE The relationship of <i>HSD11B1</i> rs45487298 and <i>H6PD</i> rs6688832 polymorphisms with obesity and MetS was studied. 31558916

2019
dbSNP: rs846906
rs846906
HSD11B1 ; HSD11B1-AS1
0.010 GeneticVariation BEFREE The rs846906-T allele was also associated with a higher risk of MetS at 3 months of follow-up (odds ratio: 3.31, 95% confidence interval: 1.53-7.17, Pcorrected=0.014). 25751397

2015
dbSNP: rs1000283
rs1000283
HSD11B1 ; HSD11B1-AS1
0.010 GeneticVariation BEFREE HSD11B1 polymorphisms (rs12086634 and rs1000283) were associated with metabolic syndrome</span> among type 2 diabetic subjects and an H6PD polymorphism (rs17368528) was a risk factor for metabolic syndrome in nondiabetic subjects. 21869537

2011