|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We conclude that the relationship between the habitual consumption of certain food groups and ADIPOQ indicates the need for further studies to develop a better understanding of this relationship; however, there was no association between the ADIPOQ + 45T> G gene polymorphism and metabolic syndrome in the group of elderly studied.
|
29313754 |
2019 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS.
|
30381540 |
2018 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
G allele of ADIPOQ rs2241766 increases the risk of MS.
|
27554120 |
2016 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Many previous studies have provided evidence that the ADIPOQ +45T>G polymorphism (rs2241766) might cause metabolic syndrome (MS).
|
27578536 |
2016 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The study also sought to identify links between two polymorphisms, -11377C>G (rs266729) and +45T>G (rs2241766) of the adiponectin gene, in relation to adiponectin levels and the metabolic syndrome.
|
24561985 |
2014 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Aim of the study was to evaluate the prevalence of metabolic symptoms in patients with PA compared to controls and the prevalence of two single nucleotide polymorphisms (SNPs), T45G and G276T, in the adiponectin gene and their relationship to metabolic syndrome (MS).
|
23590605 |
2013 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The G allele frequency of rs2241766 in metabolic syndrome patients was significantly higher than those of controls group (29.8% vs 23.3%, OR = 1.40, P = 0.033).
|
23593121 |
2013 |
|
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The SNP rs1501299 (G276T) in ADIPOQ gene was found associated with the presence of HTN in MetS (odds ratio for GG+GT vs. TT = 2.46; 95% CI: 1.14-5.3, p = 0.02), but not rs2241766 (T45G).
|
21637762 |
2011 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
<i>Results</i>: We found that CRC patients (N=75) with genotype rs266729G/C or carriers of G allele were associated with a significantly increased risk of MetS development (OR =2.9) compared to those with CC genotype (N=30).
|
28529612 |
2017 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
<i>Conclusions</i>: Our findings show that APN rs266729 G/C polymorphism is associated with lower APN levels in CRC patients, indicating that decreased circulating levels of APN may be a determinant risk factor for CRC in MetS patients.
|
28529612 |
2017 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Better designed studies with different ethnic populations and larger sample sizes are needed for assessing the relationship between ADIPOQ rs2241766 and rs266729 polymorphisms and MS in the future.
|
27554120 |
2016 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The study also sought to identify links between two polymorphisms, -11377C>G (rs266729) and +45T>G (rs2241766) of the adiponectin gene, in relation to adiponectin levels and the metabolic syndrome.
|
24561985 |
2014 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
No association was detected between SNP rs266729 and other clusters of metabolic syndrome or their traits except for HOMA-IR and fasting plasma insulin levels, p-values 0.035 and 0.004, respectively.
|
23845780 |
2013 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Then we comprehensively reviewed the association between ADIPOQ rs2241766/rs266729</span>/rs1501299 and metabolic syndrome in the Chinese populations via a meta-analysis.
|
23593121 |
2013 |
|
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A reduction in plasma SFAs could be expected to lower insulin resistance in MetS subjects who are minor allele carriers of rs266729 in ADIPOQ and rs10920533 in ADIPOR1.
|
20032495 |
2010 |
|
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The present study has confirmed that ADIPOQ -3971A>G (rs822396) and +276G>T (rs1501299) polymorphism may be clinically helpful to estimate obesity and MetS risk in North Indian Punjabi population.
|
30265726 |
2018 |
|
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
rs1501299 Polymorphism in the Adiponectin Gene and Their Association with Total Adiponectin Levels, Insulin Resistance and Metabolic Syndrome in Obese Subjects.
|
27915341 |
2016 |
|
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Then we comprehensively reviewed the association between ADIPOQ rs2241766/rs266729/rs1501299 and metabolic syndrome in the Chinese populations via a meta-analysis.
|
23593121 |
2013 |
|
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The SNP rs1501299 (G276T) in ADIPOQ gene was found associated with the presence of HTN in MetS (odds ratio for GG+GT vs. TT = 2.46; 95% CI: 1.14-5.3, p = 0.02), but not rs2241766 (T45G).
|
21637762 |
2011 |
|
rs185847354
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The I164T mutation in the adiponectin gene was a common genetic background associated with the metabolic syndrome and CAD in the Japanese population.
|
15063429 |
2004 |
|
rs185847354
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results suggest that I164T mutation is associated with hypoadiponectinemia through disturbed secretion into plasma, which may contribute to the development of the metabolic syndrome.
|
12788102 |
2003 |
|
rs185847354
|
|
|
0.030 |
GeneticVariation |
BEFREE |
All the subjects carrying I164T mutation showed some feature of metabolic syndrome, including hypertension, hyperlipidemia, diabetes, and atherosclerosis.
|
12086969 |
2002 |
|
rs17300539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In contrast, both measured genotype and cross-sectional analysis failed to detect an association between the SNP rs17300539 with traits and clusters of metabolic syndrome.
|
23845780 |
2013 |
|
rs17300539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study investigated whether the adiponectin gene promoter variant -11391 G/A (rs17300539) could predict the risk of developing traits characterizing the metabolic syndrome (MetS) and the impact of weight management.
|
18949681 |
2009 |
|
rs1259867035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS.
|
30381540 |
2018 |