| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.080 | GeneticVariation | BEFREE | In addition, the haplotypes composed of G894T and C774T polymorphisms are associated with the MetS susceptibility in Russian population. | 29907847 | 2018 |
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0.080 | GeneticVariation | BEFREE | We investigated whether genetic polymorphisms in the endothelial nitric oxide (eNOS) gene (T(786)C in the promoter region, Glu298Asp in exon 7, and 4b/4a in intron 4) or eNOS haplotypes are associated with metabolic syndrome (MetS) in obese children and adolescents. | 22983816 | 2013 |
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0.080 | GeneticVariation | BEFREE | We investigated the role of three NOS3 polymorphisms (T-786C, intron 4b/a, and G894T) in the risk of MetS using a hospital-based case-control study. | 23324585 | 2013 |
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0.080 | GeneticVariation | BEFREE | The association of eNOS G894T polymorphism with metabolic syndrome and erectile dysfunction. | 22304542 | 2012 |
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0.080 | GeneticVariation | BEFREE | NOS3 Glu298Asp polymorphism interacts with virgin olive oil phenols to determine the postprandial endothelial function in patients with the metabolic syndrome. | 21816783 | 2011 |
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0.080 | GeneticVariation | BEFREE | We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor gene was positively associated with depressive disorder (P < 0.05), but we were not able to find any significant associations of both the depressive disorder and metabolic syndrome with the remaining polymorphisms studied (methylenetetrahydrofolate reductase 677CT, methylenetet rahydrofolate reductase 1298AC, endothelial nitric oxide synthase Glu298Asp, and tyrosine hydroxylase). | 20163778 | 2010 |
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0.080 | GeneticVariation | BEFREE | Our data suggests that 894G>T plays a significant role in the mechanistic interaction between metabolic risk such as hypertension and MS, although sex-related differences may exist. | 19169496 | 2008 |
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0.080 | GeneticVariation | BEFREE | This study shows that, in a Chinese population, eNOS G894T polymorphism is associated with an elevated C-reactive protein level and MS. | 18640391 | 2008 |