| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.060 | GeneticVariation | BEFREE | <i>Results</i>: We found that CRC patients (N=75) with genotype rs266729G/C or carriers of G allele were associated with a significantly increased risk of MetS development (OR =2.9) compared to those with CC genotype (N=30). | 28529612 | 2017 |
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|
0.060 | GeneticVariation | BEFREE | <i>Conclusions</i>: Our findings show that APN rs266729 G/C polymorphism is associated with lower APN levels in CRC patients, indicating that decreased circulating levels of APN may be a determinant risk factor for CRC in MetS patients. | 28529612 | 2017 |
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|
0.060 | GeneticVariation | BEFREE | Better designed studies with different ethnic populations and larger sample sizes are needed for assessing the relationship between ADIPOQ rs2241766 and rs266729 polymorphisms and MS in the future. | 27554120 | 2016 |
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|
0.060 | GeneticVariation | BEFREE | The study also sought to identify links between two polymorphisms, -11377C>G (rs266729) and +45T>G (rs2241766) of the adiponectin gene, in relation to adiponectin levels and the metabolic syndrome. | 24561985 | 2014 |
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|
0.060 | GeneticVariation | BEFREE | No association was detected between SNP rs266729 and other clusters of metabolic syndrome or their traits except for HOMA-IR and fasting plasma insulin levels, p-values 0.035 and 0.004, respectively. | 23845780 | 2013 |
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0.060 | GeneticVariation | BEFREE | Then we comprehensively reviewed the association between ADIPOQ rs2241766/rs266729</span>/rs1501299 and metabolic syndrome in the Chinese populations via a meta-analysis. | 23593121 | 2013 |
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0.060 | GeneticVariation | BEFREE | A reduction in plasma SFAs could be expected to lower insulin resistance in MetS subjects who are minor allele carriers of rs266729 in ADIPOQ and rs10920533 in ADIPOR1. | 20032495 | 2010 |