Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE IL28B rs12980275 and HLA rs4273729 genotypes as a powerful predictor factor for rapid, early, and sustained virologic response in patients with chronic hepatitis C. 27714501

2017

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE Distribution of polymorphisms rs12979860, rs8099917 and rs12980275 IL28B in patients with chronic hepatitis C. 29264884

2017

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE IL28B rs12980275 polymorphism shows association with response to treatment in Pakistani patients with chronic hepatitis C. 25652367

2015

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE IL28B rs12980275 variant as a predictor of sustained virologic response to pegylated-interferon and ribavirin in chronic hepatitis C patients: A systematic review and meta-analysis. 25769643

2015

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE The three IL28B gene polymorphisms (CC genotype of rs12979860, TT genotype of rs8099917, and AA genotype of rs12980275) were associated with the SVR (p=0.029, p=0.016, and p=0.028, respectively) in the study patients with chronic hepatitis C treated with the combination therapy of PEGIFN α and RBV. 26614853

2015

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE To assess the role of the ss469415590 variant, compared with the known IL28B polymorphisms (rs8099917, rs12979860 and rs12980275) for predicting virological response to therapy in chronic hepatitis C, and its association with the CXCL10 chemokine serum levels - a surrogate marker of interferon-stimulated genes activation. 24308755

2014

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation GWASCAT Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. 22497812

2012

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation GWASDB Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. 22497812

2012

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation BEFREE With the screening for IL28B polymorphisms rs12980275, rs8099917 and rs12979860, which are associated with HCV chronicity and with reduced SVR rates, an important prognostic factor of the therapy of chronic hepatitis C can be easily diagnosed. 21149916

2010

dbSNP: rs12980275
rs12980275
0.870 GeneticVariation GWASDB Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. 19684573

2009