|
rs1801028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that S311C might be one of the genetic factors for symptomatic dimensions of delusions and hallucinations and might be involved in underlying clinical heterogeneity in schizophrenia and affective disorders.
|
8723039 |
1996 |
|
rs6313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In the present study, we investigated the possible influence of the T102C polymorphism of the serotonin-2A receptor gene (5-HT2A, 13q14-21) on the symptomatology of mood disorders.
|
10482339 |
1999 |
|
rs1805054
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a population-based association study, we tested the hypothesis that the allelic variant (C267T) of the human 5-HT(6) gene confers susceptibility to mood disorders.
|
10581475 |
1999 |
|
rs55814513
|
|
|
0.010 |
GeneticVariation |
BEFREE |
HhaI restriction digestion and sequencing of PCR products from four affective disorder cases showed a heterozygous Ala559Thr change.
|
10624825 |
1999 |
|
rs6313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Negative association between T102C polymorphism at the 5-HT2A receptor gene and bipolar affective disorders in Singaporean Chinese.
|
10802129 |
2000 |
|
rs28364997
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Investigation of the patients' families revealed independent segregation between the Ala559Val variant and affective disorder.
|
10889530 |
2000 |
|
rs6318
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We examined a structural variant of the serotonin 2C (5-HT2C) receptor gene (HTR2C) that gives rise to a cysteine to serine substitution in the N terminal extracellular domain of the receptor protein (cys23ser),(5) in 513 patients with recurrent major depression (MDD-R), 649 patients with bipolar (BP) affective disorder and 901 normal controls.
|
11526472 |
2001 |
|
rs5443
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The results reveal that it is not likely that the C825T polymorphism in the GNB3 gene subunit is involved in mood disorder pathogenesis.
|
11586049 |
2001 |
|
rs5443
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We studied the possible association between the prophylactic efficacy of lithium in mood disorders and the following gene variants: catechol-O-methyltransferase (COMT) G158A, monoamine oxydase A (MAO-A) 30-bp repeat, G-protein beta 3-subunit (Gbeta3) C825T.
|
11992559 |
2002 |
|
rs5443
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association study of C825T polymorphism of the G-protein b3 subunit gene with schizophrenia and mood disorders.
|
12075862 |
2002 |
|
rs1445081098
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied the possible association between the prophylactic efficacy of lithium in mood disorders and the following gene variants: catechol-O-methyltransferase (COMT) G158A, monoamine oxydase A (MAO-A) 30-bp repeat, G-protein beta 3-subunit (Gbeta3) C825T.
|
11992559 |
2002 |
|
rs2230739
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, a case-control study using the missense polymorphism, 2316A>G (Ile772Met), and the tetranucleotide repeat (TTTA)n showed no significant association with mood disorders in Japanese samples.
|
11840511 |
2002 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study has examined the association between the BDNF gene Val66Met polymorphism and mood disorders, age of onset and suicidal behavior in a Chinese sample population.
|
14673216 |
2003 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study has examined the association between the BDNF gene Val66Met polymorphism and mood disorders, age of onset and suicidal behavior in a Chinese sample population.
|
14673216 |
2003 |
|
rs6313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Lack of association between the 5HT2A receptor polymorphism (T102C) and unipolar affective disorder in a multicentric European study.
|
12957335 |
2003 |
|
rs1382119307
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A recently identified functional polymorphism in the beta(1)-adrenergic receptor (G1165C) leading to the amino acid variation Gly389Arg was associated with an enhanced coupling to the stimulatory G(s)-protein and increased adenylyl cyclase activation, disturbances which are often observed in affective disorders.
|
12815745 |
2003 |
|
rs1801253
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A recently identified functional polymorphism in the beta(1)-adrenergic receptor (G1165C) leading to the amino acid variation Gly389Arg was associated with an enhanced coupling to the stimulatory G(s)-protein and increased adenylyl cyclase activation, disturbances which are often observed in affective disorders.
|
12815745 |
2003 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.
|
15770238 |
2005 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.
|
15770238 |
2005 |
|
rs734312
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Haplotype analysis revealed a common GTA haplotype, formed by SNPs 684C/G, 1185C/T and 1832G/A, conferring risk for affective disorders.
|
15473915 |
2005 |
|
rs147634553
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis revealed a common GTA haplotype, formed by SNPs 684C/G, 1185C/T and 1832G/A, conferring risk for affective disorders.
|
15473915 |
2005 |
|
rs1801206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis revealed a common GTA haplotype, formed by SNPs 684C/G, 1185C/T and 1832G/A, conferring risk for affective disorders.
|
15473915 |
2005 |
|
rs1801213
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis revealed a common GTA haplotype, formed by SNPs 684C/G, 1185C/T and 1832G/A, conferring risk for affective disorders.
|
15473915 |
2005 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This variant and two previously reported BDNF SNPs (C270T and Val66Met) were genotyped in 295 patients with AD, 108 with AFDs, 96 with posttraumatic stress disorder (PTSD), 84 with schizophrenia, 327 with alcohol and/or drug dependence, and 250 normal control subjects.
|
16649215 |
2006 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This variant and two previously reported BDNF SNPs (C270T and Val66Met) were genotyped in 295 patients with AD, 108 with AFDs, 96 with posttraumatic stress disorder (PTSD), 84 with schizophrenia, 327 with alcohol and/or drug dependence, and 250 normal control subjects.
|
16649215 |
2006 |