Gene: MGMT ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12917
rs12917
MGMT ; LOC105378560
0.010 GeneticVariation BEFREE Logistic regression analysis showed that Leu</span>84Phe of MGMT gene and pathological grade were independent risk factors for the increase of TMZ resistance in patients with malignant gliomas. 28409559

2017
dbSNP: rs2308321
rs2308321
MGMT
0.010 GeneticVariation BEFREE This study aims to investigate the associations of O<sup>6</sup>-methylguanine-DNA methyltransferase (MGMT) genetic polymorphisms (Leu84Phe and Ile143Val) with temozolomide (TMZ) resistance and prognosis of patients with malignant gliomas. 28409559

2017