DisGeNET - a database of gene-disease associations

Maternal hypertension, C0565599

Variant: rs1217691063 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1217691063

MTHFR

0.030

GeneticVariation

BEFREE

Meta-analysis of studies comparing women with and without hypertension in pregnancy for the C677T MTHFR polymorphism.

15311088

2004

dbSNP:

rs1217691063

MTHFR

0.030

GeneticVariation

BEFREE

Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: a meta-analysis.

21346782

2012

dbSNP:

rs1217691063

MTHFR

0.030

GeneticVariation

BEFREE

Several epidemiological studies have investigated the associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with hypertension (H) or hypertension in pregnancy (HIP).

24505291

2014