We carried out association studies and multivariate analyses including other candidate causal factors of HP such as the M235T variant of the angiotensinogen (AGT) gene, prepregnancy body mass index (BMI), and family history of hypertension in Japanese subjects.
The M235T variant of the angiotensinogen gene and the body mass index are useful markers for prevention of hypertension in pregnancy: a tree-based analysis of gene-environment interaction.
To determine whether a state of hypertension in pregnancy in the Japanese can be predicted in the early period based on detection of the M235T variant of the angiotensinogen gene, alone or with other factors.