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rs751377893
|
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0.100 |
GeneticVariation |
BEFREE |
No differences were found for FV G1691A or homozygous MTHFR mutations between neonates with CSVT and their mothers, compared to controls.
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31025572 |
2019 |
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rs751377893
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this case-control study, we aimed to determine the frequency of prothrombin G20210A and factor V Leiden (FVL) G1691A polymorphisms and protein C, protein S, and antithrombin III deficiencies in the East Algerian population and to investigate whether these genetic factors are associated with VTE.
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26304686 |
2017 |
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rs751377893
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study was carried out in 100 patients with hemophilia A. Genotyping for factor V Leiden (FVL) G1691A, prothrombin G20210A, MTHFR C677T, and A1298C mutations was conducted using a real time-polymerase chain reaction (RT-PCR) assay.
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26891731 |
2016 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
Significant differences were found in the frequencies of the genotypes for both the FVL (G1691A) (P<10(-3), odds ratio [OR]=17.4, confidence interval [CI]=6.20-59) and prothrombin (G20210A) (P=.007, OR=5.11, CI=1.30-29) polymorphisms between RVO patients and healthy controls.
|
24630828 |
2014 |
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rs751377893
|
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0.100 |
GeneticVariation |
BEFREE |
Factor V Leiden (FVL) G1691A, Prothrombin (PT) G20210A and methylenetetrahydrofolate reductase (MTHFR) C677T and A128C mutations were evaluated in children with moderate-severe hemophilia A (n = 51) and controls (n = 25).
|
22411997 |
2014 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
We determined whether the presence of the factor prothrombin gene G20210A variant, factor V gene G1691A mutation (factor V Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms may be risk factors for vascular complications in individuals with SCD.
|
23992124 |
2013 |
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rs751377893
|
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0.100 |
GeneticVariation |
BEFREE |
It has been hypothesized that thrombophilic G1691A factor V Leiden (FVL), if detected well ahead in time among recurrent miscarriages may be a treatable.
|
22990475 |
2013 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The genetic polymorphisms C677T and A1298C relating to the enzyme methylenetetrahydrofolate reductase (MTHFR), a clotting Factor V Leiden mutation (1691G→A substitution of Factor V Leiden), and the mutant prothrombin 20210A allele were analyzed in this study.
|
22924497 |
2012 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
Detection of FVL (G1691A) and FII (G20210A) mutations was carried out using PCR with sequence specific primers.
|
21269570 |
2011 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The frequency of FVL G1691A and ACE D allele in T2DM patients with microalbuminuria were 1.6 and 57%, respectively and in normoalbuminuric T2DM patients were 4.9 and 58.3%, respectively (P > 0.05).
|
20853144 |
2011 |
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rs751377893
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0.100 |
GeneticVariation |
BEFREE |
To find association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D), angiotensinogen (AGT) T704C, methylenetetrahydrofolate reductase (MTHFR) C677T and factor V Leiden (FVL) G1691A polymorphisms with pre-eclampsia (PE) in North Indian women.
|
21564405 |
2011 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
Eighty DVT patients with the mean age of 42.07 +/- 13.0 years including 44 women and 36 men and 100 sex-matched healthy individuals with the mean age of 37.63 +/- 13.3 years from Kermanshah Province of Iran with ethnic background of Kurd were studied for FVL c.1691G>A, prothrombin g.20210G>A and MTHFR c.677C>T by PCR-restriction fragment length polymorphism (RFLP) method using MnlI, HindIII and HinfI restriction enzymes, respectively.
|
20479641 |
2010 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The G1691A mutation of the factor V gene (factor V Leiden) and the G20210A mutation of the prothrombin gene as risk factors in thrombotic microangiopathies.
|
19448164 |
2009 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The most common genetic defect associated with deep vein thrombosis (DVT) is a mutation in the Factor V gene (G1691A), known as Factor V Leiden (FVL).
|
19604111 |
2009 |
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rs751377893
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|
0.100 |
GeneticVariation |
BEFREE |
In a 12-member, 3-generation kindred with conjoint inheritance of G1691A factor V Leiden (FVL) and G20210A prothrombin gene (PTG) mutations, identified through a proband with amaurosis fugax and his father with nonarteritic ischemic optic neuropathy (NAION), the authors' hypothesis was that ocular thrombosis was a diagnostic window to familial thrombophilia-thrombosis.
|
18796459 |
2009 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The protein C (PC), protein S, antithrombin activities, homocysteine levels, and factor V Leiden (FVL) G1691A and prothrombin G20210A mutations were evaluated in 191 patients with VTE and 191 controls.
|
17895505 |
2008 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
We used polymerase chain reaction techniques to characterize the thrombophilic FVL G1691A gene mutation.
|
17582408 |
2008 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The frequency of the thrombophilic genetic variants factor V Leiden (FVL) G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T in acutely symptomatic ambulatory patients with idiopathic pulmonary embolism (PE) has not been measured.
|
16574759 |
2006 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
Factor V Leiden (FVL) G1691A, methylenetetrahydrofolate reductase (MTHFR) C677T, and factor II (FII) G20210A mutations are three important causes of thrombophilia, the condition that might be related to infertility and recurrent spontaneous abortion (RSA).
|
16450127 |
2006 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
We determined if the presence of the factor V gene G1691A mutation (factor V Leiden), the prothrombin gene G20210A variant, and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism may be risk factors for vascular complications in individuals with SCD.
|
16906320 |
2006 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
If we had sequenced the F5 gene in patients homozygous for this haplotype, in order to locate the possible causal polymorphism, we would have found that 16 (76%) patients were homozygous or heterozygous for a missense mutation in exon 10 (1691G --> A), which predicts the replacement of Arg506 by Gln in one of the cleavage sites for activated protein C, a mutation that we now know as the FVL mutation.
|
15054398 |
2004 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
Maternal, paternal, and fetal DNA were genotyped for the methylenetetrahydrofolate reductase (MTHFR) C677T and Factor V Leiden (FVL) G1691A SNPs.
|
15097012 |
2004 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
To analyze the influence of the prothrombotic gene mutation factor V G1691A (factor V Leiden) and prothrombin G20210A on the risk of a first episode of catheter-related deep venous thrombosis (DVT) in a group of patients with breast cancer treated with chemotherapy.
|
15033664 |
2004 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The aim of our study was to evaluate the association of thrombophilic factor V G1691A mutation (factor V Leiden) and G20210A prothrombin mutation with the disease.
|
15187864 |
2004 |
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rs751377893
|
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|
0.100 |
GeneticVariation |
BEFREE |
The system eliminates the false positive FVL G1691A results associated with other PCR/RFLP caused by rare confounding mutations adjacent to restriction endonuclease recognition sites.
|
12745655 |
2003 |