|
rs1273593548
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> Osteosarcoma cancer cell line MG-63 was transfected with Ras gene with G12V and Y40C site mutation.
|
31126199 |
2019 |
|
rs756673959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> Osteosarcoma cancer cell line MG-63 was transfected with Ras gene with G12V and Y40C site mutation.
|
31126199 |
2019 |
|
rs367597251
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> Osteosarcoma cancer cell line MG-63 was transfected with Ras gene with G12V and Y40C site mutation.
|
31126199 |
2019 |
|
rs1800896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, a statistically significant association between the IL-10 -1082A/G (rs1800896) genotype and poor survival in osteosarcoma</span> patients was observed.
|
26503210 |
2016 |
|
rs8103992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An expression quantitative trait locus for cartilage intermediate layer protein 2 (CILP2), rs8103992, was significantly associated with osteosarcoma risk after adjustment for multiple comparisons (odds ratio, 1.35; 95% CI, 1.16-1.56 [P = 7.93×10<sup>-5</sup> and P<sub>adjusted</sub> =.034]).
|
30311632 |
2018 |
|
rs780673045
|
|
|
0.020 |
GeneticVariation |
BEFREE |
As a whole, 11 of 29 (38%) analyzed OS presented alterations in some of the analyzed G1 to S-phase checkpoint genes.
|
15167009 |
2004 |
|
rs861539
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Association between the DNA Repair Gene XRCC3 rs861539 Polymorphism and Risk of Osteosarcoma: a Systematic Review and Meta-Analysis
|
28345844 |
2017 |
|
rs1799782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Besides, no significant association of rs25487, rs1799782, and rs25489 with OS was observed.
|
30464596 |
2018 |
|
rs25489
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Besides, no significant association of rs25487, rs1799782, and rs25489 with OS was observed.
|
30464596 |
2018 |
|
rs699947
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By stratified analysis, AA genotype of rs699947 was associated with an increased risk of osteosarcoma</span> in those with shorter age, males and a family history of cancer, and GG genotype of rs2010963 was correlated with an increased risk of osteosarcoma in those with shorter age, females and a family history of cancer.
|
25550863 |
2014 |
|
rs2010963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By stratified analysis, AA genotype of rs69994</span>7 was associated with an increased risk of osteosarcoma</span> in those with shorter age, males and a family history of cancer, and GG genotype of rs2010963 was correlated with an increased risk of osteosarcoma in those with shorter age, females and a family history of cancer.
|
25550863 |
2014 |
|
rs531564
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CG +$ GG genotype of hsa-miR-124a rs531564 had decreased risk for OS and affected prognosis of OS.
|
27540978 |
2016 |
|
rs4938723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared with wild-type TT genotype, the variant genotypes of rs4938723 TC/CC were significantly associated with increased OS risk (TC vs. TT: OR, 1.97 [95% CI: 1.40-2.55], P = 0.021; CC vs. TT: OR, 2.76 [95% CI: 2.00-3.53], P = 0.009; TC + CC vs. TT: OR, 2.16 [95% CI: 1.61-2.70], P = 0.006), consistent with its decreased effect on plasma miR-34b (TC vs. TT: -0.32 (-0.43, -0.21), P < 0.001; CC vs. TT: -0.70 (-0.84, -0.56), P < 0.001; TC + CC vs. TT: -0.42 (-0.53, -0.32), P < 0.001).
|
24063968 |
2014 |
|
rs1061970
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CT genotype and C allele of COL1A1 at rs1061970, and CG genotype and G allele of COL1A1 at rs2075559 are associated with decreased susceptibility to osteosarcoma</span> in the Chinese population.
|
24072491 |
2014 |
|
rs2075559
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CT genotype and C allele of COL1A1 at rs1061970, and CG genotype and G allele of COL1A1 at rs2075559 are associated with decreased susceptibility to osteosarcoma in the Chinese population.
|
24072491 |
2014 |
|
rs756340448
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
|
rs11615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
|
rs3212986
|
|
|
0.030 |
GeneticVariation |
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
|
rs171140
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
|
rs1799793
|
|
|
0.100 |
GeneticVariation |
BEFREE |
ERCC1 (C118T (rs11615) and C8092A (rs3212986)) and ERCC2 (A751C (rs171140) and G312A (rs1799793)) polymorphisms were analysed in 44 patients with osteosarcoma, who were treated with cisplatin based neoadjuvant chemotherapy.
|
29980176 |
2018 |
|
rs1253660442
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Even though the role of single nucleotide polymorphisms of ATIC in chemotherapy-induced tumor necrosis has not been investigated yet, the ATIC 347C>G polymorphism may influence the levels of adenosine after MTX treatment, which may affect the histologic response of osteosarcoma.
|
28267080 |
2017 |
|
rs2372536
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Even though the role of single nucleotide polymorphisms of ATIC in chemotherapy-induced tumor necrosis has not been investigated yet, the ATIC 347C>G polymorphism may influence the levels of adenosine after MTX treatment, which may affect the histologic response of osteosarcoma.
|
28267080 |
2017 |
|
rs17655
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Excision repair cross-complementing (ERCC) group 2 (XPD; rs13181 and rs1799793), group 5 (XPG; rs17655) and group 1 (XPA; rs3212986 and rs11615) polymorphisms were analyzed in a group of 130 homogenously treated patients with high-grade osteosarcoma, for association with event-free survival (EFS), using the Kaplan-Meier plots and log-rank test.
|
21826087 |
2012 |
|
rs11615
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Excision repair cross-complementing (ERCC) group 2 (XPD; rs13181 and rs1799793), group 5 (XPG; rs17655) and group 1 (XPA; rs3212986 and rs11615) polymorphisms were analyzed in a group of 130 homogenously treated patients with high-grade osteosarcoma, for association with event-free survival (EFS), using the Kaplan-Meier plots and log-rank test.
|
21826087 |
2012 |
|
rs12894467
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four polymorphisms in pre-miRNAs at 14q32 miRNA cluster were associated with osteosarcoma risk in the Spanish population (rs12894467, rs61992671, rs58834075 and rs12879262).
|
30337581 |
2018 |