|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
these 3 men were diagnosed as hyperhomocysteinemia and MTHFR C677T homozygous TT genotype.
|
30633186 |
2019 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
He was found as having MTHFR C677T homozygote and plasminogen activator inhibitor-1 4G/5G heterozygote gene mutation with high homocysteine level of 22.90 µmol/L, and he was diagnosed as hyperhomocysteinemia.
|
31409160 |
2019 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase C677T variant and hyperhomocysteinemia in subarachnoid hemorrhage patients from India.
|
29926428 |
2018 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Association of vitamin B12 mediated hyperhomocysteinemia and methylenetetrafolate reductase (C677T) gene polymorphism with cognitive impairment: A population based study from North India.
|
30245375 |
2018 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genotyping of hyperhomocysteinemia associated MTHFR polymorphisms C677T (rs1801133) and A1298C (rs1801131) was done by PCR-restriction fragment length polymorphism.
|
29600437 |
2018 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genotyping of hyperhomocysteinemia associated MTHFR polymorphisms C677T (rs1801133) and A1298C (rs1801131) was done by PCR-restriction fragment length polymorphism.
|
29600437 |
2018 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study provided evidence that hyperhomocysteinemia (HHcy) and MTHFR C677T polymorphism were associated with IS.
|
29390494 |
2017 |
|
rs1188383936
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Risk factors reviewed include myeloproliferative neoplasms (MPNs) and their related gene mutations, anti-phospholipid syndrome, paroxysmal nocturnal haemoglobinuria (PNH), hyperhomocysteinaemia and 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T mutation, factor V Leiden (FVL) and prothrombin G20210A mutations, inherited anti-thrombin, protein C and protein S deficiencies, pregnancy and puerperium, poverty, and family history.
|
27734511 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To evaluate the genetic polymorphism of MTHFR C677T among β-TM patients and its prospective contribution to Hhcy and related oxidative changes.
|
27187171 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MTHFR C677T and hyperhomocysteinemia have been identified as risk factors for autism worldwide.
|
27755291 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To investigate the distribution of MTHFR C677T and A1298C as well as PON1 Q192R gene polymorphisms, known to be involved in hyperhomocysteinemia-related cardiovascular risk, in elite athletes.
|
26282718 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MTHFR C677T is a common gene polymorphism that has been shown to be associated with hyperhomocysteinemia.
|
28002332 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The interaction analysis showed that age and peripheral arterial disease played an interactive role in the association between HHcy and AAA, while drinking status played an interactive role in the association between MTHFR C677T polymorphism and AAA.
|
26865327 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The meta-analysis suggests that MTHFR C677T genetic polymorphism is significantly associated with susceptibility to IS, which provides evidence supporting hyperhomocysteinemia as a risk factor for stroke.
|
26776436 |
2016 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To investigate the distribution of MTHFR C677T and A1298C as well as PON1 Q192R gene polymorphisms, known to be involved in hyperhomocysteinemia-related cardiovascular risk, in elite athletes.
|
26282718 |
2016 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There are limited data on the role of methylenetetrahydrofolate reductase C677T polymorphism and hyperhomocysteinemia as risk factors for cerebral venous thrombosis in Iranian population.
|
26083986 |
2015 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the OpenArray platform for genetic testing of blood donors and to assess the genotype frequencies of nucleotide-polymorphisms (SNPs) associated with venous thrombosis (G1691A and G20210A), hyperhomocysteinemia (C677T, A1298C), and hereditary hemochromatosis (C282Y, H63D and S65C) in blood donors from Sao Paulo, Brazil.
|
25955572 |
2015 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Of the 58 patients, 30 had factor V Leiden mutation (5 homozygous, 25 heterozygous), 16 had prothrombin gene mutation, 24 had methylenetetrahydrofolate reductase C677T mutation (5 homozygous, 19 heterozygous), 18 had protein C deficiency, 17 had protein S deficiency, 14 had antithrombin III deficiency and 13 had hyperhomocysteinaemia.
|
25326427 |
2015 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
With an excellent sensitivity and a modest specificity, C677T could be a useful screening marker for severe HHcy.
|
24459043 |
2015 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms, which are associated with hyperhomocysteinemia and nitric oxide (NO) deficiency (which is related to atherothrombosis and cerebral ischemia), have not been studied in moyamoya disease.
|
25098357 |
2014 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A thrombophilic evaluation was performed, revealing hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) variants (C677T and A1298C).
|
24923843 |
2014 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
5,10-methylenetetrahydrofolate reductase (MTHFR) is a folate-dependent enzyme that catalyzed remethylation of homocysteine (Hcy) and the MTHFR C677T polymorphism makes the MTHFR enzyme thermolabile causing hyperhomocysteinemia.
|
24052451 |
2014 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The MTHFR C677T polymorphism was not related to SVD and LVD, although the TT genotype was an important determinant of hyperhomocysteinemia.
|
25031284 |
2014 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
to investigate if NAFLD, in subjects referred for nutritional assessment and counselling, has any difference of prevalence and severity when associated with isolated MTHFR A1298C polymorphism and hyperhomocysteinemia.
|
24488901 |
2014 |
|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A thrombophilic evaluation was performed, revealing hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) variants (C677T and A1298C).
|
24923843 |
2014 |