Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10009409
rs10009409
LOC105377273 ; LOC107986286
T 0.700 GeneticVariation GWASCAT A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. 25217961

2014
dbSNP: rs10009409
rs10009409
LOC105377273 ; LOC107986286
T 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016

2018
dbSNP: rs1001179
rs1001179
CAT
0.010 GeneticVariation BEFREE Furthermore, stratified analyses revealed a significant association between the rs1001179 polymorphism and prostate cancer in all models except the homozygote comparison. 27449288

2016
dbSNP: rs10012
rs10012
CYP1B1 ; CYP1B1-AS1
0.020 GeneticVariation BEFREE A common C-G-C-C-G-A haplotype for rs2567206-rs2551188-rs2617266-rs10012-rs1056836-rs1800440 showed an inverse association with PCa risk in Hispanic Caucasians (OR = 0.19, P = 0.04, 95% CI = 0.04-0.95) and with aggressive disease status (i.e. 18544568

2008
dbSNP: rs10012
rs10012
CYP1B1 ; CYP1B1-AS1
0.020 GeneticVariation BEFREE In summary, this meta-analysis suggests that Leu432Val polymorphism is associated with ovarian cancer, lung cancer, and endometrial cancer risk; Asn453Ser and Arg48Gly polymorphisms are associated with endometrial cancer risk among Caucasians, Ala119Ser polymorphism is associated with prostate cancer risk, and Ala119Ser polymorphism is associated with breast cancer risk in Caucasians. 25475389

2015
dbSNP: rs1004030
rs1004030
MMP14
T 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016

2018
dbSNP: rs1004072779
rs1004072779
ERG
0.010 GeneticVariation BEFREE Significant association of TMPRSS2-ERG fusion-positive PCa was found with rare variants in the genes for POLI [variant F532S: P = 0.0011; odds ratios (OR), 4.62; 95% confidence interval (95% CI), 1.84-11.56] and ESCO1 (variant N191S: P = 0.0034; OR, 4.27; 95% CI, 1.62-11.28). 19861517

2009
dbSNP: rs10046
rs10046
CYP19A1 ; MIR4713HG
0.010 GeneticVariation BEFREE The combination of the TTTA long repeats and the minor alleles of rs10046 in CYP19A1 and rs2077647 in ESR-alpha was a high risk for prostate cancer despite greater than or equal to 60 mg isoflavones/day. 19952760

2010
dbSNP: rs10069690
rs10069690
TERT
0.010 GeneticVariation BEFREE The T allele of the intron 4 SNP (rs10069690) was found to be significantly associated with a decreased risk for an aggressive form of PCa (OR=0.76; 95% CI: 0.59-0.97; P=0.030). 25738283

2015
dbSNP: rs10086908
rs10086908
PCAT1 ; LOC105375751
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs10086908
rs10086908
PCAT1 ; LOC105375751
T 0.700 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE We showed statistically significant association of the A allele of rs1447295 (OR [CI 95%] = 1.96 [1.37-2.81], P<0.0001) and the T allele of rs10090154 (OR [CI 95%] = 2.14 [1.41-3.26], P<0.0001) with CaP. 23628314

2014
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE Therefore, this meta-analysis demonstrated that 8q24 polymorphisms (rs6983267 T>G, rs1447295 C>A, rs16901979 C>A, rs6983561 A>C and rs10090154 C>T) were associated with the susceptibility to PCa, which held the potential biomarkers for PCa risk. 29158792

2017
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE Four GWAS replication SNPs (rs2660753, rs13254738, rs10090154, rs2735839) and seven flanking SNPs were associated with CaP aggressiveness (P < 0.05) in three genomic regions: One at 3p12 (EA), seven at 8q24 (5 AA, 2 EA), and three at 19q13 at the kallilkrein-related peptidase 3 (KLK3) locus (two AA, one AA and EA). 22549899

2013
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE For northern Chinese men rs16901966, rs1447295, rs11986220 and rs10090154 at 8q24 (region 1, region 2) are associated with prostate cancer and prostate cancer related clinical covariates. 22099997

2012
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE The cumulative effects test of risk alleles (rs rs1983891, rs339331, rs16901966, rs1447295 and rs</span>10090154) showed an increasing risk to PCa in a frequency-dependent manner (ptrend=0.001), and men with more than 3 risk alleles had the most significant susceptibility to PCa (OR=1.99, p=0.001), compared with those who had one risk allele (OR=1.17, p=0.486). 26537068

2016
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE We genotyped three variants associated with prostate cancer (rs10090154, rs13254738, and rs7000448), one associated with both prostate and colorectal cancer (rs6983267), and one associated with breast cancer (rs13281615) in a series of 1,499 breast cancer cases and 1,390 controls. 18349290

2008
dbSNP: rs10090154
rs10090154 		0.070 GeneticVariation BEFREE The risk alleles rs16901966, rs1447295 and rs10090154 were associated with age at diagnosis and tumor stage as compared with controls, while rs16901966 was associated with aggressive PCa (OR 1.43, 95% CI 1.01-2.03, p=0.042). 24377597

2014
dbSNP: rs1011970
rs1011970
CDKN2B-AS1
T 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs10122495
rs10122495
UBAP2
T 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016

2018
dbSNP: rs1012477
rs1012477
PER3
0.010 GeneticVariation BEFREE Our results showed that at least one SNP in nine core circadian genes (rs885747 and rs2289591 in PER1; rs7602358 in PER2; rs1012477 in PER3; rs1534891 in CSNK1E; rs12315175 in CRY1; rs2292912 in CRY2; rs7950226 in ARNTL; rs11133373 in CLOCK; and rs1369481, rs895521, and rs17024926 in NPAS2) was significantly associated with susceptibility to prostate cancer (either overall risk or risk of aggressive disease), and the risk estimate for four SNPs in three genes (rs885747 and rs2289591 in PER1, rs1012477 in PER3, and rs11133373 in CLOCK) varied by disease aggressiveness. 19934327

2009
dbSNP: rs1016342
rs1016342
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT Multiple newly identified loci associated with prostate cancer susceptibility. 18264097

2008
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies new prostate cancer susceptibility loci. 21743057

2011
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015