Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.050 | GeneticVariation | BEFREE | Our findings indicate that HIF1A rs11549465 polymorphism may not independently play a significant role in the occurrence of prostate cancer. | 28415653 | 2017 |
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0.050 | GeneticVariation | BEFREE | The HIF1A +1772 C>T (rs11549465) polymorphism was genotyped, using DNA isolated from peripheral blood, in 1490 male subjects (754 with prostate cancer and 736 controls cancer-free) through Real-Time PCR. | 24090974 | 2014 |
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0.050 | GeneticVariation | BEFREE | The current findings suggest that HIF1A P582S polymorphism correlates with urinary cancers risk in Caucasian population, while A588T polymorphism may increase the risk of urinary cancers in Asian population and prostate cancer. | 23723982 | 2013 |
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0.050 | GeneticVariation | BEFREE | No altered PCa risk was associated with the rs11549465 and rs2057482 polymorphism. | 23042446 | 2012 |
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0.050 | GeneticVariation | BEFREE | Our data suggest that homozygous HIF1A P582S mutation confers significant susceptibility to prostate cancer. | 16998808 | 2007 |
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0.030 | GeneticVariation | BEFREE | The current findings suggest that HIF1A P582S polymorphism correlates with urinary cancers risk in Caucasian population, while A588T polymorphism may increase the risk of urinary cancers in Asian population and prostate cancer. | 23723982 | 2013 |
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0.030 | GeneticVariation | BEFREE | However, the combined variant genotypes of rs2057482 and rs11549467 were associated with increased PCa risk (OR=2.10; 95%CI=1.23-3.57 among subjects carrying three or more risk alleles). | 23042446 | 2012 |
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0.030 | GeneticVariation | BEFREE | No significant differences were found between the frequencies of A588T mutation in prostate cancer patients and controls. | 16998808 | 2007 |
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0.010 | GeneticVariation | BEFREE | However, the combined variant genotypes of rs2057482 and rs11549467 were associated with increased PCa risk (OR=2.10; 95%CI=1.23-3.57 among subjects carrying three or more risk alleles). | 23042446 | 2012 |