Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making. 27272900

2016
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Clinical and pathological characteristics of Hispanic BRCA-associated breast cancers in the American-Mexican border city of El Paso, TX. 25628955

2015
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Protein stability versus function: effects of destabilizing missense mutations on BRCA1 DNA repair activity. 25748678

2015
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Addressing health disparities in Hispanic breast cancer: accurate and inexpensive sequencing of BRCA1 and BRCA2. 26543556

2015
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Prevalence and type of BRCA mutations in Hispanics undergoing genetic cancer risk assessment in the southwestern United States: a report from the Clinical Cancer Genetics Community Research Network. 23233716

2013
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Prevalence and characterization of BRCA1 and BRCA2 germline mutations in Chinese women with familial breast cancer. 21614564

2012
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Toward classification of BRCA1 missense variants using a biophysical approach. 20378548

2010
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays. 20516115

2010
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR BRCA1 germline mutations and tumor characteristics in Chinese women with familial or early-onset breast cancer. 18512148

2009
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis. 17308087

2007
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Functional impact of missense variants in BRCA1 predicted by supervised learning. 17305420

2007
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Prevalence of BRCA mutations and founder effect in high-risk Hispanic families. 16030099

2005
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Classification of BRCA1 missense variants of unknown clinical significance. 15689452

2005
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations. 14534301

2003
dbSNP: rs786203663
rs786203663
BRCA1
TCACT 0.700 CausalMutation CLINVAR Frequency of germline and somatic BRCA1 mutations in ovarian cancer. 9796975

1998