| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
C | 0.700 | CausalMutation | CLINVAR | Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. | 29446198 | 2018 |
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|
C | 0.700 | CausalMutation | CLINVAR | Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. | 27616075 | 2017 |
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|
C | 0.700 | CausalMutation | CLINVAR | Central European BRCA2 mutation carriers: birth cohort status correlates with onset of breast cancer. | 24156927 | 2014 |
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|
C | 0.700 | CausalMutation | CLINVAR | Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. | 23569316 | 2013 |
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|
C | 0.700 | CausalMutation | CLINVAR | A comprehensive focus on global spectrum of BRCA1 and BRCA2 mutations in breast cancer. | 24312913 | 2013 |
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|
C | 0.700 | CausalMutation | CLINVAR | BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica. | 21895635 | 2012 |
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|
C | 0.700 | CausalMutation | CLINVAR | Variation in breast cancer risk associated with factors related to pregnancies according to truncating mutation location, in the French National BRCA1 and BRCA2 mutations carrier cohort (GENEPSO). | 22762150 | 2012 |
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|
C | 0.700 | CausalMutation | CLINVAR | Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype. | 18182994 | 2008 |
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|
C | 0.700 | CausalMutation | CLINVAR | The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators. | 10969800 | 2000 |