Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria. 18240302

2008
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR The intermediate filament protein, vimentin, is a regulator of NOD2 activity. 22684479

2013
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR NOD2 exonic variations in Iranian Crohn's disease patients. 21274544

2011
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. 15571588

2004
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. 15024686

2004
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR Genotyping for NOD2 genetic variants and crohn disease: a metaanalysis. 19713276

2009
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations. 15770725

2005
dbSNP: rs2066844
rs2066844
NOD2
T 0.700 SusceptibilityMutation CLINVAR Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study. 21548950

2011
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. 15571588

2004
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? 15190267

2004
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. 15198989

2004
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Genotyping for NOD2 genetic variants and crohn disease: a metaanalysis. 19713276

2009
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Variants of CARD15, TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: high frequency of the CARD15 1007fs. 18489434

2008
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. 12512038

2003
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. 15024686

2004
dbSNP: rs2066845
rs2066845
NOD2
C 0.700 SusceptibilityMutation CLINVAR Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study. 21548950

2011
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Variants of CARD15, TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: high frequency of the CARD15 1007fs. 18489434

2008
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Monocyte-derived dendritic cells from Crohn patients show differential NOD2/CARD15-dependent immune responses to bacteria. 18240302

2008
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. 15024686

2004
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. 11385576

2001
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. 15571588

2004
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? 15190267

2004
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR The intermediate filament protein, vimentin, is a regulator of NOD2 activity. 22684479

2013
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. 11425413

2001
dbSNP: rs2066847
rs2066847
NOD2
GC 0.700 SusceptibilityMutation CLINVAR Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. 15198989

2004