rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The results suggest these polymorphisms, especially rs1966265 and rs2981578, might be candidate pharmacogenomics factors to the response and prognosis prediction for individualized CET-based chemotherapy in breast cancer patients.
|
30359238 |
2018 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
A significant association with BC risk was found with SNP rs2981578 (unadjusted per-allele odds ratio = 1.20, 95% confidence interval 1.03-1.41, P(trend) = 0.02), with the odds ratio estimate similar to that reported in European and Asian subjects.
|
19223389 |
2009 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Thus, the apparent increased risk of developing ERα positive breast cancer seems not to be caused by rs2981578 alone.
|
24265722 |
2013 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Our results suggest that the A allele and AA genotype of SNP rs2981578 appear to be protective factors associated with breast cancer, while the CT genotype of SNP rs3750817 is a putative risk factor.
|
21822685 |
2012 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
This meta-analysis of case-control studies provides strong evidence that FGFR2 (rs2981582, rs2420946 and rs2981578) polymorphisms were significantly associated with the BC risk.
|
27966449 |
2017 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Our results suggest that the increased breast cancer risk associated with SNP rs2981578 is due to increased FGFR2 signaling activity in stromal fibroblasts, possibly also involving paracrine FGF10 signaling.
|
21767389 |
2011 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Polymorphic variants of 2q35-rs13387042, 3p24-rs4973768, 17q23-rs650490 and FGFR2-rs2981578 were analyzed to test for their association with breast cancer susceptibility.
|
22287734 |
2012 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Results from the current meta-analysis indicates that three novel functional polymorphisms (rs11200014, rs2981579, and rs2981578) in the promoter of FGFR2 gene are associated with breast cancer susceptibility and might be a potential biomarkers for breast cancer risk.
|
23124475 |
2012 |
rs2981578
|
|
|
0.790 |
GeneticVariation |
BEFREE |
We first validated that the SNPs rs12922061, rs2290203, and rs2981578 were associated with overall breast cancer risk in southeast Chinese women, with the per-allele OR of 1.209 (95%CI: 1.064-1.372), 1.176 (95%CI: 1.048-1.320), and 0.852 (95%CI: 0.759-0.956), respectively.
|
27705907 |
2016 |
rs2981578
|
|
C |
0.790 |
GeneticVariation |
GWASCAT |
Association analysis identifies 65 new breast cancer risk loci.
|
29059683 |
2017 |
rs2981578
|
|
C |
0.790 |
GeneticVariation |
GWASCAT |
Genome-wide association study of breast cancer in the Japanese population.
|
24143190 |
2013 |