Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE The results suggest these polymorphisms, especially rs1966265 and rs2981578, might be candidate pharmacogenomics factors to the response and prognosis prediction for individualized CET-based chemotherapy in breast cancer patients. 30359238

2018

dbSNP: rs2981578
rs2981578
C 0.790 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683

2017

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE This meta-analysis of case-control studies provides strong evidence that FGFR2 (rs2981582, rs2420946 and rs2981578) polymorphisms were significantly associated with the BC risk. 27966449

2017

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE We first validated that the SNPs rs12922061, rs2290203, and rs2981578 were associated with overall breast cancer risk in southeast Chinese women, with the per-allele OR of 1.209 (95%CI: 1.064-1.372), 1.176 (95%CI: 1.048-1.320), and 0.852 (95%CI: 0.759-0.956), respectively. 27705907

2016

dbSNP: rs2981578
rs2981578
C 0.790 GeneticVariation GWASCAT Genome-wide association study of breast cancer in the Japanese population. 24143190

2013

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE Thus, the apparent increased risk of developing ERα positive breast cancer seems not to be caused by rs2981578 alone. 24265722

2013

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE Our results suggest that the A allele and AA genotype of SNP rs2981578 appear to be protective factors associated with breast cancer, while the CT genotype of SNP rs3750817 is a putative risk factor. 21822685

2012

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE Polymorphic variants of 2q35-rs13387042, 3p24-rs4973768, 17q23-rs650490 and FGFR2-rs2981578 were analyzed to test for their association with breast cancer susceptibility. 22287734

2012

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE Results from the current meta-analysis indicates that three novel functional polymorphisms (rs11200014, rs2981579, and rs2981578) in the promoter of FGFR2 gene are associated with breast cancer susceptibility and might be a potential biomarkers for breast cancer risk. 23124475

2012

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE Our results suggest that the increased breast cancer risk associated with SNP rs2981578 is due to increased FGFR2 signaling activity in stromal fibroblasts, possibly also involving paracrine FGF10 signaling. 21767389

2011

dbSNP: rs2981578
rs2981578
0.790 GeneticVariation BEFREE A significant association with BC risk was found with SNP rs2981578 (unadjusted per-allele odds ratio = 1.20, 95% confidence interval 1.03-1.41, P(trend) = 0.02), with the odds ratio estimate similar to that reported in European and Asian subjects. 19223389

2009